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Staff
Dr. Andy Baxevanis is a senior scientist leading NHGRI's Computational Genomics Unit.
… Dr. Baxevanis is the  director of Computational Biology  for the National Institutes of Health's (NIH) … is centered on probing the interface between genomics and developmental biology, using computational approaches to … genomics, computational biology, bioinformatics, developmental biology … Dr. Andy Baxevanis is a senior …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… diseases they study. For Shawn Burgess, Ph.D., head of the Developmental Genomics Section, the rationale comes down to the fact that fish regenerate. "We study the developmental biology of hearing," Dr. Burgess said. "Humans don't …
News Release
Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… other biological processes vital to understanding human biology and disease. … The studies highlight the data … genomes greatly help to inform our understanding of human biology." "One way to describe and understand the human … patterns shared by all three species, particularly for developmental genes. Investigators showed that the ways in …
Staff
Dr. Edward Giniger is an adjunct investigator in NHGRI's Genetics and Molecular Biology Branch.
… J., Kuzina, I., Gu, Q. and Giniger. E. Cdk5 regulates developmental remodeling of mushroom body neurons in … an adjunct investigator in NHGRI's Genetics and Molecular Biology Branch. … Staff …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… can better understand how the appearance, behavior and biology of living things have changed over time. As DNA … studies are uncovering new behavioral, neurological and developmental pathways and genes that are shared or related … that are commonly used as surrogates in studying human biology. These include the rat, puffer fish, fruit fly, sea …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… (NICHD) are collaborating to support a new initiative, the Developmental Genotype-Tissue Expression ( dGTEx ) Project. … Laboratory, Data Analysis, and Coordinating Center for the Developmental Genotype-Tissue Expression Project Pediatric … Biospecimen Procurement Center (BPC) supporting the Developmental Gene Expression (dGTEx) Project Ruth L. …
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… By comparing when and what epigenetic changes mark certain developmental periods in humans and dogs, researchers hope to … the research. All mammals experience the same overarching developmental timeline: birth, infancy, youth, puberty, … a genetic system for studies that inform human health and biology," said Dr. Ostrander. … Read the study … NHGRI …
File
… quantitation and accuracy to use routinely in genome biology and function • Apply lessons learned from DNA … and de novo sequencing • Expand understanding of genome biology and function • Genotype to phenotypes • Enable single … project period up to 3 years • RFA R21 (Exploratory/Developmental Research) up to $200K DC/year; project period …
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… 9, 2015 July 2014 Strategic Planning Workshop Structure of Biology of Biology of Science of Effectiveness of Genomes Genomes … origins of proteins, biochemical pathways, core metazoan developmental program, etc .) • Defining the genomic basis of …
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… cost and accuracy to use routinely in studies of genome biology and function, and in biomedical research in general . … Human Genome Project, and other efforts, NHGRI transformed biology by making genomics mainstream , with genomics now … project period of up to 3 years • R21 (Exploratory/Developmental Research) ; up to $200 K direct costs/year; …