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A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
… Locus … A locus is the specific physical location of a gene or other … Locus, Allele, DNA Polymorphism, Gene, Chromosome … A locus, as related to genomics, is a physical site or location … interest), somewhat like a street address. The plural of locus is loci. … A locus is the specific physical location of a gene or other …
Educational Resources
A trait is a specific characteristic of an organism.
… Trait … A trait is a specific characteristic of an organism. … Gene, Gene Expression, Phenotype, Genotype … A trait, as related to genetics, is a specific characteristic … of both. Traits can be qualitative (such as eye color) or quantitative (such as height or blood pressure). A given …
News Release
Researchers funded by NIH have completed a detailed atlas documenting stretches of human DNA that influence gene expression.
… documenting the stretches of human DNA that influence gene expression - a key way in which a person's genome gives rise to an observable trait, like hair color or disease risk. This atlas is a … atlas is the culmination of work from the Genotype-Tissue Expression (GTEx) Consortium, established to catalog how …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… has awarded eight grants as part of the Genotype-Tissue Expression (GTEx) project to explore how human genes are … the role that genomic variation plays in modulating that expression. … An Atlas of Human Gene Expression The GTEx awards will contribute to a resource …
Research Funding
Building upon a foundation of quantitative genetics laid over a century ago, applying modern genomic approaches to resolve how genetic and non-genetic factors shape variation in human diseases and traits.
… goal of human genetics is to decompose the sources of trait variation into constituent causal factors. The hope is … or influence those traits. Although the foundation of quantitative genetics was laid over a century ago, there … the interplay of genetic and non-genetic factors on trait variation. These issues have recently risen to the fore …
Talking Glossary
Dominant, as related to genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait.
… genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait. … genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait. Individuals inherit two versions of each gene, known …
Educational Resources
A polygenic trait is one whose phenotype is influenced by more than one gene.
… Polygenic Trait … A polygenic trait is one whose phenotype is influenced by more than one … A polygenic trait is a characteristic, such as height or skin color, that … A polygenic trait is one whose phenotype is influenced by more than one …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… Gene Expression … Gene expression is the process by which the information encoded in … Gene expression is the process by which the information encoded in … non-coding RNA molecules that serve other functions. Gene expression be thought of as an “on/off switch” to control …
News Release
NIH researchers have created a data resource show how differences in an individual's genome can affect gene activity and contribute to disease.
… by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and … It gives us unique insights into how people differ in gene expression in tissues and organs." NIH launched the GTEx … GTEx investigators used a methodology - expression quantitative trait locus (eQTL) analysis - to gauge how …
Educational Resources
Recessive Traits and Alleles is a quality found in the relationship between two versions of a gene.
… genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait. Individuals inherit two versions of each gene, known … as alleles, from each parent. In the case of a recessive trait, the alleles of the trait-causing gene are the same, …