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Educational Resources
Genomic variation refers to diversity in gene frequencies.
… Genomic Variation … Genomic variation refers to diversity in gene frequencies. … Genetic Variation, Genetic Testing, … effects. … Genomic variation refers to diversity in gene frequencies. … Educational Resources …
Educational Resources
A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next.
… Copy Number Variation (CNV) … A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next. … Chromosomes, Disease, DNA, Gene Variation … Copy number variation (abbreviated CNV) …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… DNA sequences near genes that control when and how much a gene is turned on and off, or expressed, are often extremely important for gene activity. … To paint a clearer picture of how such variation affects gene activity, Fernando Pardo Manuel de …
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… of Cardiovascular Disease in Africans Americans Study (GENE-FORECAST®) study is developing a community-based cohort … the biological significance of ancestry-related genomic variation in African-Americans. … GENE-FORECAST® will test the working hypothesis that …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… regulated in different tissues, and the role that genomic variation plays in modulating that expression. … An Atlas of Human Gene Expression The GTEx awards will contribute to a resource … inherited spelling changes in the DNA code - may influence gene activity and lead to disease. The grants will add data …
Research Funding
The Genomic Variation Program supports large-scale studies of human genetic variation.
… the sequence of DNA among individuals are called genetic variation. Genomic variation explains some of the differences among people, such … studies and databases relating variation to differences in gene function and regulation and to clinical effects. … The …
News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
… of the human genome that are associated with skin color variation in some African populations, opening new avenues … with skin color. Hands of people with skin color variation. Variation in skin color is one of the most striking features …
Fact Sheet
Genomic variation accounts for some of the differences among people, including important aspects of their health and susceptibility to diseases.
… The Big Picture   Genomic variation reflects the differences in a person’s DNA compared … comprehensive framework that aims to account for genomic variation across human populations, thereby reducing biases … health and disease (e.g., by disrupting the function of a gene that encodes an important protein). One of the most …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… Center Multiscale functional characterization of genomic variation in human developmental disorders HG011996 Hyejung … Duke University High-throughput functional annotation of gene regulatory elements and variants critical to complex … resource of functional elements, TF footprints and gene regulatory interactions HG011986 Ansuman Satpathy …
Educational Resources
Gene regulation is the process of turning genes on and off.
Gene Regulation … Gene regulation is the process of turning genes on and off. … Gene Expression, Genes, DNA, Transcription Factors … Gene regulation is the process used to control the timing, …