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Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … have inherited mutations in certain cancer-susceptibility genes have a lifetime risk of cancer that is significantly …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… Breast cancer is the second most common cancer in women after skin cancer. Each year, approximately 200,000 women in the United … Breast cancer is a common disease. Each year, approximately 200,000 … cancer - caused by a mutant gene passed from parents to their children - is rare. Estimates of the incidence of …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted research on mice with a rare disease similar to one in humans, hoping their findings may eventually help … not insert where it would elevate the expression of nearby genes and it did not cause liver cancer. The researchers …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research Institute (NHGRI) … the mutation profiles of CCEC tumors are sometimes similar to other types of uterine cancer, namely serous endometrial … her team specialize in basic research aimed at identifying genes that are mutated (changed) in the tumors of patients …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified … potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease. They … of therapy. The scientists found recurrent mutations in 32 genes, including nine that were not previously known to be …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United States. An estimated 40 to 50 percent of Americans who live to age 65 will have skin cancer at least once. … type of cancer in the United States. An estimated 40 to 50 percent of Americans who live to age 65 will have skin …
Genetic Disorders
Colon cancer is a malignant tumor of the large intestine that affects both men and women.
… Colon cancer, a malignant tumor of the large intestine, affects … States, approximately 160,000 new cases of colorectal cancer are diagnosed each year. … of colon cancer. The risk of inheriting these mutated genes from an affected parent is 50 percent for both males …
Educational Resources
A first degree relative is a family member who shares about 50 percent of their genes with a particular individual in a family.
… is a family member who shares about 50 percent of their genes with a particular individual in a family. … Genetic Disorders, Ancestry, Healthcare, Genealogy, Genes … is a family member who shares about 50 percent of their genes with a particular individual in a family. …
News Release
The TCGA network describes uterine and bile duct cancer.
… The Cancer Genome Atlas (TCGA), a program co-funded by the National Cancer Institute and NHGRI, has greatly improved our … - outlining the molecular similarities between different cancer patients and cancer types, as well as documenting what … TCGA's dataset can provide a more complete picture of how to prevent, diagnose and treat specific cancer types. The …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
… Cancer … Cancer is a group of diseases characterized by uncontrolled … Cancer, Cell Division, Mutation, DNA Error, Metastasis, … a genomic change (or mutation) that allows the cell to divide and multiply unchecked. Additional mutations can … ultraviolet rays). In certain cases, mutations in cancer genes are inherited, which increases a person’s risk of …