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Educational Resources
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
… Genetic Mutation, Base Pairs, DNA Sequence …
Educational Resources
A nonsense mutation is the substitution of a single base pair that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid.
… Nonsense Mutation, Missense Mutation, Base Pair, Genetic Code, Genetic Mutation …
Educational Resources
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
… A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during … A mutation is a change in the DNA sequence of an organism. Mutations can result from errors in DNA replication during … exposure to mutagens or a viral infection. Germline mutations (that occur in eggs and sperm) can be passed on to …
Educational Resources
A point mutation is when a single base pair is altered.
… base pair is added, deleted or changed. While most point mutations are benign, they can also have various functional …
Educational Resources
A missense mutation is when the change of a single base pair causes the substitution of a different amino acid in the resulting protein.
… position in the resulting protein. Some missense mutations alter the function of the resulting protein. …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… that these cells are prone to increased numbers of genetic mutations. A new study by scientists at the National Human … were reprogrammed and in cells that were subcloned. M ost genetic variants detected in the iPSCs and subclones were … Findings: Induced pluripotent stem cells don't increase genetic mutations …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… researchers and their collaborators have identified mutations in the TAF1 gene. They've also demonstrated that … a 45 percent five-year relative survival rate. "Genomic mutations that contribute to clear cell endometrial cancer … cells from patients with CCEC. Their goal was to identify genetic mutations in CCEC tumor cells that are absent from …
Educational Resources
Deletion is a type of mutation involving the loss of genetic material.
… Deletion is a type of mutation involving the loss of genetic material. … Genetic Mutation, Base Pair, DNA, Chromosome … Deletion is a type of mutation involving the loss of genetic material. …
News Release
Researchers sequence the genomes of healthy participants, then analyze the data to find presumed, mutations that might lead to a genetic condition.
… find a mutation in the genomic sequence of a person with a genetic disease, they sequenced the genomes of healthy … then analyzed the data to find "putative," or presumed, mutations that would almost certainly lead to a genetic condition. … that 34 had the specific condition linked to their genetic mutation. These findings indicate that 3 percent or …
Genetic Disorders
Fragile X syndrome is an inherited intellectual disability caused by a mutation in the FMR1 gene.
… this may be the only sign of the problem. A specific genetic test (polymerase chain reaction [PCR]) can now be … Genetic Disorders …