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Educational Resources
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases.
… Genome-Wide Association Studies (GWAS) … A genome-wide association study (GWAS) is an approach used in genetics research to … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene … A genome-wide association study (abbreviated GWAS) is a research …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… Genome-wide association studies involve scanning markers across the … A genome-wide association study is an approach that involves rapidly … With the completion of the Human Genome Project in 2003 and the International HapMap Project … computerized databases that contain the reference human genome sequence, a map of human genetic variation and a set …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… international team of researchers has conducted the first study of its kind to look at the genomic underpinnings of … clusters in families. Researchers at the National Human Genome Research Institute (NHGRI), part of the National … States and globally. This is the first study to use a Genome-Wide Association Study (GWAS) to investigate the …
Clinical Studies
The IDENTIFY Study is a study exploring how prenatal blood test results for the baby might also detect cancer in the mother.
… and provides us with the most useful information for our study. Most hospitals do not have the same MRI capabilities. … or non-reportable NIPT result, you can still join the study. You will not have to travel to the NIH to participate. … place in or near your hometown to follow up on your study results. In most cases, the next step is to have a …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… in the Division of Genomic Medicine at the National Human Genome Research Institute (NHGRI), which helps administer the … For the last decade, scientists have used genome-wide association studies (GWAS) to study the role that genomic … funding, Simona Volpi, Division of Genomic Medicine, Genome Wide Association Studies, GWAS, genome expression in …
Staff
Dr. Lucia Hindorff is the Lead Extramural Training Program Director in the Training, Diversity, and Health Equity Office at the National Human Genome Research Institute.
… and Health Equity (TiDHE) Office at the National Human Genome Research Institute (NHGRI). She previously served as … and the NHGRI scientific lead for the online NHGRI Genome-wide Association Study catalog. In her time at NHGRI, she has … studies, with application to the NHGRI-EBI GWAS Catalog. Genome Biol . 2018 Feb 15;19(1):21. doi: …
News Release
NIH will fund researchers to develop computational approaches to figure out which differences in DNA make people more susceptible to disease.
… genetic variants - in the less-studied regions of the genome that are responsible for regulating gene activity. A … associated with a disease, researchers typically conduct a genome-wide association study (GWAS), which compares the genomes of … NIH supports approaches to discovering DNA differences in genome’s regulatory regions …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… on Genomics and Global Health within the National Human Genome Research Institute, National Institutes of Health. … of methods for multivariable analysis of genome-wide association data as well as investigation into global … D. B. 2007. Detection of gene × gene interactions in genome-wide association studies of human population data. …
Educational Resources
Personalized medicine is an emerging practice of medicine that uses an individual's genetic profile to guide decisions made in regard to the prevention, diagnosis, and treatment of disease.
… Human Genome Project, Genetic Counseling, Genome-Wide Association Studies (GWAS), Pedigree, Pharmacogenomics, … medicine is being advanced through data from the Human Genome Project. …
Clinical Research
The INSIGHTS study is exploring sickle cell disease in adults.
… Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS) study is exploring sickle cell disease in adults by looking … The goal of this study is to learn how these factors influence the onset and … are investigating the disease as a whole and studying the wide range of complications that sickle cell patients …