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Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… served on the scientific advisory boards of the center for stem cell and regenerative medicine, the national disease … process of generating all of the different types of blood cells (erythrocytes, lymphocytes, platelets, etc.) … cells are derived from a small population of pluripotent hematopoietic stem cells . as pluripotent hematopoietic stem
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… its make-up is different among cell types, even among cells that are similar. investigators from two national human … what to do - among three types of cells : mouse embryonic stem (es) cells , embryonic fibroblasts and hematopoietic progenitors. they combined hundreds of …
Staff
Dr. Paul Liu is NHGRI's deputy scientific director and a senior investigator in NHGRI's Translational and Functional Genomics Branch. ​
… during leukemia development by microarray analysis with cells from cbfb-myh11 knock-in mice, and identified … in cbfb and made novel findings regarding its role in hematopoietic stem cell production (bresciani, blood in press). overall the …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… in 2009 with a report that menin is required for in vitro hematopoietic differentiation of mouse embryonic stem cells and this role of menin is mediated by its ability to …
News Release
NIH researchers have identified a treatment that significantly decreases the risk of stroke in children with a rare genetic disease called Deficiency of Adenosine Deaminase Type 2 (DADA2).
… some dada2 patients at other institutions had received hematopoietic stem cell transplant ( stem cells that give rise to all other blood cells ), which …
Staff
Dr. Raman Sood is the director of the Zebrafish Core at the National Human Genome Research Institute. ​
… zebrafish to generate novel mutants for several important hematopoietic genes. through the study of mutations in gata1 … emergence and differentiation of hematopoietic stem cells and developing new therapeutics for blood disorders by …
Staff
Dr. Tyra Wolfsberg is the associate director of the Bioinformatics and Scientific Programming Core at the National Human Genome Research Institute. ​
… possess complex cell types such as neurons and muscle cells, are our oldest animal relatives; she anticipates that … understanding of tissue regeneration, allorecognition, and stem cell biology. dr. wolfsberg's group has also developed … dunbar ce, and persons da. sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… elkahloun demonstrated that exosomes derived from cancer cells can affect the transcriptomes of surrounding cells, … roberts dd. a function-blocking cd47 antibody suppresses stem cell and egf signaling in triple-negative breast cancer. … x, liu pp, jin j, chen j. pbx3 and meis1 cooperate in hematopoietic cells to drive acute myeloid leukemias …