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Staff
Dr. James Inglese is an adjunct investigator in NHGRI's Genetics and Molecular Biology Branch.
… james inglese directs the assay development and screening technology laboratory within the division of … and international chemical biology consortia. … high throughput technologies enable assays of biochemical, …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… at the nhgri, dr. elkahloun started applying large scale screening methods to identify genes associated with … patel n, elkahloun a, lee mj, trepel j, ferrer m, pacak k. high-throughput screening for the identification of new …
Archive
high-throughput screening finds surprising properties for antioxidants … …
File
… for functional studies • Encourage development of high - throughput assays and animal models for these genes AJHG … Measures with National Quality Forum (NQF) • Tumor-based screening for Lynch syndrome followed by cascade screening in …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… on an organism lacking it. such larger scale - termed high-throughput - gene targeting in an animal model could be … lab.) this produced mutations in 82 of the 83 genes. in screening embryos by fluorescent polymerase chain reaction (a …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… identify new genetic targets against the disease. current screening of possible anti-metastasis compounds is based on … against cancer cell lines in laboratory dishes. such high-throughput screening has identified thousands of drug …
News Release
A team from the NIH has surmounted a major obstacle to testing potential drug therapies for a rare, genetic condition called Gaucher disease.
… they identified the small molecule compound through high-throughput screening , which tests hundreds of thousands of small …
Staff
Stacie Anderson is the director of the Flow Cytometry Core at the National Human Genome Research Institute. ​
… goal of providing all nhgri investigators with access to high quality flow cytometry services to enhance the scope and … transcription profiles including scrnaseq, as well as high throughput screening of enhancer regions. … gomez-rodriguez j, wohlfert …
Staff
Dr. Shawn Burgess is a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
… genes. the burgess group developed new techniques for high-throughput identification of retroviral integration sites, … over which genes are inactivated. as a result, targeted screening in a vertebrate is now possible for the first time, …
Staff
Dr. Raman Sood is the director of the Zebrafish Core at the National Human Genome Research Institute. ​
… and developing new therapeutics for blood disorders by high-throughput chemical screening . animal models play a critical role in …