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News Release
Researchers from NHGRI, Oxford University and other National Institutes of Health centers have developed and tested a new method to predict hospital-acquired infections involving five other important pathogens.
… Ganguly, Ph.D. … A passive monitoring tool can detect hospital-acquired infections early and potentially help reduce contagion. … …
Clinical Research
An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 Pandemic (At-home Participation).
… study to help better understand the interaction between infections and mitochondrial disease. If you are interested, …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… to a weaker and less diverse antibody response to viral infections. The study, published in Frontiers in Immunology … that B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress. “Our … are affected. “For children with mitochondrial disorders, infections can be life threatening or they can worsen the …
Clinical Research
A Longitudinal Natural History Study of Children with Mitochondrial Disease (at the NIH Clinical Center).
Clinical Research
The Metabolism, Infection and Immunity (MINI) Section aims to define the relationship between infection, immunity and clinical decline in individuals with mitochondrial disease.
Fact Sheet
Viruses are bundles of genetic material wrapped in a protein coat that can infect living things.
… it leaves the host cell to infect other cells. Some viral infections cause no symptoms. However, when many viral …  are known to cause disease in humans, including: Acquired immunodeficiency syndrome (AIDS) Viral agent: Human … , they do not seem to cause disease. But circovirus infections in other mammals such as dogs and pigs can cause …
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… increasing. However, these vaccines work by preventing new infections, and the long interval between infection and …
Genetic Disorders
Cystic fibrosis is a genetic disease that causes the body to produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas.
… is the most common cause of chronic and fatal lung infections for people with CF. Scientists hope to use their … genetic sequence to develop innovative drugs for treating infections caused by P. aeruginosa. Gene Database Speeds …
Staff
Dr. Gordon-Lipkin is a researcher and child neurologist with expertise in neurodevelopmental disabilities in the Metabolism, Infection and Immunity (MINI) Section.
… in pediatrics from the Mount Sinai Kravis Children’s Hospital in New York City; fellowship and subspeciality … and Kennedy Krieger Institute, respectively, where she acquired expertise in neurogenetic and neuroimmune disorders. … of mitochondrial disease to better understand why infections lead to neurologic decline in these patients. She …
Staff
Dr. Pamela Schwartzberg is a adjunct investigator in NHGRI's Genetic Disease Research Branch.
… mouse genetics. After an internship at Boston Children's Hospital, she did a fellowship with Harold Varmus, M.D., at … in a primary immunodeficiency associated with recurrent infections and fulminant responses to Epstein-Barr Virus …