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News Release
A new study highlights how genomic mutations that cause mitochondrial disease may also compromise affected people's immune response.
… disease may also compromise affected people's immune response. … disease in T-cells. T-cells play important roles in human immune response. The mutations resulted in an increased risk … NHGRI study highlights role of mitochondria in immune response … disease may also compromise affected people's immune response. …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… One of the first human studies on how mitochondrial function impacts immune cells to guide future treatments. … in Immunology was led by researchers at the National Human Genome Research Institute (NHGRI), who analyzed gene activity of immune cells in children with mitochondrial disorders and …
News Release
A new study offers insights into why some people's hair goes gray in response to a serious illness or chronic stress.
… offers insights into why some people's hair goes gray in response to a serious illness or chronic stress. Researchers … to hair color and the genes that control the body's immune system. They published their findings May 3, 2018, in … of the Genetic Disease Research Branch at NIH's National Human Genome Research Institute (NHGRI). "These results may …
News Release
Researchers at NHGRI have discovered an immune mechanism in humans that perceives threats and was found only in plants.
… don't seem to have much in common. When it comes to their immune systems, however, they might be more similar than their exteriors suggest. Researchers at the National Human Genome Research Institute (NHGRI) have discovered an immune mechanism in humans, known as a "guard" mechanism, …
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
… The billions of microbes that reside on human skin - probably more than 10 billion microbial cells on … the skin microbiota plays an intricate role in the human immune system, actually directing many immune functions … head of the Microbial Genomics Section of the National Human Genome Research Institute (NHGRI), and Yasmine Belkaid, …
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… to six research institutions to create a database of human cellular responses, the Library of Integrated … the Data and Signature Generating Centers. The National Human Genome Research Institute (NHGRI) and the National … and analyze cellular function and molecular activity in response to perturbing agents - such as drugs and genetic …
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… genomic switches of a blood cell are key to regulating the human immune system. The findings, published in Nature today, open … Genomics and Metabolic Genetics Branch at the National Human Genome Research Institute (NHGRI). Autoimmune diseases occur when the immune system mistakenly attacks its own cells, causing …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… according to a new study by researchers at the National Human Genome Research Institute (NHGRI), part of the National … occurred, but hypothesize that it may be related to stress response. "When you're stressed, stress hormones such as adrenaline are released, resulting in a fight or flight response," Mr. Lienert said. "If you are then unable to fight …
Clinical Research
A Longitudinal Natural History Study of Children with Mitochondrial Disease (at the NIH Clinical Center).
… can affect many different parts of the body, including the immune system and its ability to respond to infection. … how Inborn Errors of Metabolism affect the function of the immune system. …
Educational Resources
An antibody is a protein component of the immune system that circulates in the blood, recognizes foreign substances like bacteria and viruses, and neutralizes them.
… An antibody is a protein component of the immune system that circulates in the blood, recognizes … Immune System, Bacteria, Virus, Blood, Circulation, Disease, … An antibody is a protein component of the immune system that circulates in the blood, recognizes … An antibody is a protein component of the immune system that circulates in the blood, recognizes …