Search Results

1 - 10 of 53
News Release
NIH researchers identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood.
… same gene in patients with a similar type of blood vessel inflammation. … The NIH group first encountered a patient … deaminase 2 (ADA2). Without it, abnormalities and inflammation in blood vessel walls result. The researchers … nodosa (PAN). PAN is a form of vasculitis, an inflammation of medium and small arteries that leads to pain, …
Genetic Disorders
Familial Mediterranean Fever is an inherited disease, characterized by recurrent attacks of fever, inflammation, painful, swollen joints, and ankle rash.
… disease, characterized by recurrent attacks of fever, inflammation of the abdominal lining (peritonitis), inflammation of the lining surrounding the lungs , painful, … are symptom-free. Other symptoms that may occur include inflammation of the lining surrounding the heart …
Staff
Dr. Ayo Doumatey is a Research Fellow and Laboratory Manager at NHGRI's Center for Research on Genomics and Global Health.
… KS, Huang H, Zhou J, et al. Relationships among obesity, inflammation, and insulin resistance in African Americans and … and Global Health, genetic epidemiology, complex diseases, inflammation … Ayo Doumatey, Center for Research on Genomics … and Global Health, genetic epidemiology, complex diseases, inflammation … Dr. Ayo Doumatey is a Research Fellow and …
News Release
Genomic analyses turned up genes that belong to inflammatory pathways.
… chronic, recurrent, multi-focal osteomyelitis (CRMO), or inflammation of the bone. "Children who have CRMO can have inflammation in one bone, and then in a different bone," said … case, the effect leads to a form of cell death that causes inflammation. Dr. Kastner had a hunch from the scientific …
File
… gastrointestinal issues, which may be caused by excess inflammation. We’ve always known that germline R U N X1 … but it seems that it may have an even bigger role in inflammation and the immune system. You might have learned … into the R U N X1 Research Program’s (RRP) webinar on Inflammation and R U N X1 (RRP is a 501c non-profit …
File
… genes identified to date 3 pathways: protein processing, inflammation and lipids Alzheimer’s Disease Introduction 4 • …
File
… tissue regeneration and wound healing by regulating inflammation and cell proliferation Document 50 To receive …
News Release
NHGRI researchers investigated the Behcet's disease using Illumina's Immunochip.
… is a disease that destroys blood vessels through systemic inflammation, manifesting as painful oral and genital ulcers, as well as vision destroying inflammation of the eyes. Research suggests the disease …
News Release
NHGRI researchers have discovered clues to the possible cause of recurring, non-contagious fevers and sores that affect only children. Several genes have been implicated with the syndrome, known as PFAPA syndrome (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis), which could lead to new treatments.
… Prabarna Ganguly, Ph.D. … Study shows mutations in inflammation-related genes are associated with PFAPA syndrome … inflammatory diseases: Behçet’s disease, which causes inflammation of blood vessels, and canker sores. Each illness … association was with the gene IL12A , which encodes an inflammation-related protein that is used by the immune …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… of FMF include recurrent fevers, arthritis, rashes and inflammation of the tissues that line the heart, lungs, and … example, in the event of an infection). Pyrin increases inflammation and the production of inflammation-related molecules. In contrast, FMF patients …