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News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… for clues about how the body signals the lack of oxygen in melanoma skin cancer, national institutes of health (nih) … that were associated with the amount of time it took the melanoma to move from the original tumor to the rest of the … their findings february 6, 2017, in pigment cell and melanoma research . "these newly identified genes and genetic …
Staff
Dr. Stacie Loftus is a staff scientist in the Genomics, Development and Disease Section of NHGRI's Genetic Disease Research Branch.
… during an individual's lifetime that give rise to melanoma , a highly lethal skin cancer with increasing … niches, and hypoxic conditions found in metastatic melanoma tumors. melanocytes respond by altering gene … in addition, well-characterized expression profiles for melanoma cells have been identified that correlate highly …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… united states. the most virulent form of skin cancer is melanoma . in some parts of the world, especially in western countries, the number of people who develop melanoma is increasing faster than any other cancer. in the united states, for example, the number of new cases of melanoma has more than doubled in the past 20 years. … three …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… molecular profiling technologies, osteosarcoma profiling, melanoma profiling, breast cancer profiling, technology … molecular profiling technologies, osteosarcoma profiling, melanoma profiling, breast cancer profiling, technology …
Staff
William J. Pavan, Ph.D. is the chief of NHGRI's Genetic Disease Research Branch.
… is associated with waardenburg syndrome iv and with human melanoma , and also identified the lysosomal transmembrane … somatic mutations of sox10  are rarely present in human melanoma, the most lethal form of skin cancer in the united … they went on to demonstrate that reduction of sox10 causes melanoma cells to undergo cellular growth arrest and …
Partner with NHGRI
NHGRI's technologies, inventions and discoveries are available for licensing.
… register description   other research materials human melanoma cell lines with erbb4 mutations dhhs reference no.: … e-229-2010 lead inventor: yardena samuels, ph.d. human melanoma metastasis cell line with isocitrate dehydrogenase …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… of the prostate, endometrium, lung, bladder, and breast; melanoma , and fanconi anemia. these research efforts are …
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… from some types of advanced cancers, namely myeloma, melanoma and sarcoma. it would be one of the first studies in …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… migration - by performing cell culture assays with human melanoma cells. some of the compounds showed "significant …
News Release
NIH grants aim to gauge if genomics can be used to help diagnose diabetes, manage heart disease and guide cancer clinicians to the most effective drugs.
… tests lung cancer, breast cancer, colorectal cancer and melanoma patients for known gene mutations, which in turn, …