Dr. Edward Giniger is an adjunct investigator in NHGRI's Genetics and Molecular Biology Branch.
… Information processing in the brain is done by specialized neural circuits. Every neuron has a long process, an "axon", that … understand these processes in humans, Dr. Giniger studies neural circuits of fruit flies, a model system that allows …
NHGRI researchers have shown that areas of the genome related to brain development harbor variants that may account for behavioral differences among different dog lineages.
… nerve cells, known as neurons, organize themselves to form neural circuits during the early stages of development. Some of the …
In June 2013, the Supreme Court determined that DNA in its natural form cannot be patented.
Dr. Sudre is an Associate Investigator in Dr. Philip Shaw's Neurobehavioral Clinical Research within the Social and Behavioral Research Branch
… states. Previously, Dr. Sudre was part of the Human Rehab Neural Engineering Lab at the University of Pittsburgh, … Branch. The main goal of his research is to integrate neural, genomic and behavioral data, with the added dimension … symptoms through the integration of childhood genomic, neural, and cognitive features. Mol Psychiatry 26, 4046–4054. …
Dr. Lawrence Brody is a senior investigator in NHGRI's Social and Behavioral Research Branch and director of NHGRI's Division of Genomics and Society.
… major area of investigation focuses on the genetics of neural tube defects (NTDs) and other birth defects. NTDs and … variants in genes involved in vitamin B12 metabolism to neural tube defects. A major focus of the Brody laboratory … synthetase is a maternal genetic risk factor for neural tube defects: Report of the birth defects research …
Dr. Philip Shaw is an investigator in the Social and Behavioral Research Branch at the National Human Genome Research Institute.
… studies: We are attempting to translate our genomic and neural discoveries into clinically useful tools. Firstly, we … novel treatments for ADHD on our understanding of the neural bases of remission. For example, if remission from ADHD is reflected by a convergence of early neural differences towards more typical dimensions, then …
Dr. Elise Feingold is a scientific program manager in NHGRI's Division of Genome Sciences.
… et al. Comparative analysis of regulatory information and circuits across distant species . Nature , 512(7515):453-6. … al. Identification of functional elements and regulatory circuits by Drosophila modENCODE . Science , …
The NIH-funded Integrative Human Microbiome Project presented at the International Human Microbiome Congress.
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… research. During zebrafish development, a cluster of neural cells called the "posterior lateral line primordium" … of metastasizing human cancer. The cluster of zebrafish neural cells - which will help the adult fish sense water …
William J. Pavan, Ph.D. is the chief of NHGRI's Genetic Disease Research Branch.
… interventions. Dr. Pavan's group first discovered the neural crest cell transcription factor SOX10 , which is … of the HMG-box transcription factor SOX10 result in neural crest stem cell defects in mice that accurately model … complex component Magoh controls brain size by regulating neural stem cell division. Nature Neurosci , 13:551-558. …