Search Results
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… A comprehensive analysis of the genomes of nearly 500 papillary thyroid carcinomas (PTC) - the most common form of thyroid cancer - …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… PS, Hager GL, Cheng SY. Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
…  TCGA study improves understanding of genetic drivers of thyroid cancer  (2014)  Rare kidney tumor provides insights …
Staff
Dr. Bell is a senior investigator at the National Human Genome Research Institute's Cancer Genetics and Comparative Genomics Branch.
… first whole-exome sequencing studies of serous endometrial carcinomas, in which they discovered frequent mutations in … consequences and potential clinical relevance. Endometrial carcinomas can be classified into numerous histological … subtypes including serous, clear cell, and endometrioid carcinomas, as well as uterine carcinosarcomas. Serous and …
News Release
Genomicists and clinicians are beginning to offer patients genetic testing for a list of treatable diseases apart from the one that brought them into the clinic.
… several health problems, including up to a 95% chance of thyroid cancer and tumors in the thyroid area. While the tumors are not always cancerous, they … Bloodwork and a biopsy confirmed that Bryant had thyroid cancer. Soon after, he scheduled surgery to remove …
Genetic Disorders
Down syndrome is a chromosomal condition related to chromosome 21.
… people who have Down syndrome have low activity of the thyroid gland (hypothyroidism) - an organ in the lower neck … to prevent hearing loss and chronic infections. Low thyroid levels are more common in infants who have Down syndrome. It is recommended that thyroid level testing be performed at least yearly. Some …