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Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
… Sickle cell disease is a group of inherited red blood cell disorders. … Sickle cell disease is the most … from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) are smooth and …
News Release
Researchers used whole genome sequence data to investigate the origin of the mutation that causes "sickling" of red blood cells.
… the origin of the mutation that causes sickling of red blood cells, which reduces their ability to carry oxygen and can …
Fact Sheet
Currently, there are different gene therapy approaches available through clinical trials.
… Hemoglobin types and sickle cell disease  Your red blood cells contain hemoglobin , a protein that carries oxygen. Red …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… After postdoctoral work at NIH's National Heart, Lung and Blood Institute, Dr. Bodine founded the Hematopoiesis Section … process of generating all of the different types of blood cells (erythrocytes, lymphocytes, platelets, etc.) … undifferentiated hematopoietic cells differentiate into red blood cells. Perturbations of this process cause a …
Educational Resources
A somatic cell is any cell of the body except sperm and egg cells.
… Somatic Cells … A somatic cell is any cell of the body except sperm and egg cells. … Cell, Chromosome, Diploid, Mutation, Germ Line … Somatic cells are the cells in the body other than sperm and egg …
Educational Resources
A cell cycle is a series of events that takes place in a cell as it grows and divides.
… mitosis, and completes its division. The resulting cells, known as daughter cells, each enter their own interphase and begin a new round …
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… of Health (NIH) have discovered the genomic switches of a blood cell are key to regulating the human immune system. The … occur when the immune system mistakenly attacks its own cells, causing inflammation. Different tissues are affected … investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system. ​ … …
Educational Resources
The cell membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside environment.
… membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside … … Plasma Membrane, Proteins, Glycoproteins, Lipid Bilayer, Cells … The cell membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside …
Educational Resources
A cell is the basic building block of living things.
… … A cell is the basic building block of living things. All cells can be sorted into one of two groups: eukaryotes and … not. Plants and animals are made of numerous eukaryotic cells, while many microbes, such as bacteria, consist of single cells. An adult human body is estimated to contain between 10 …
Educational Resources
A stem cell is a cell with the potential to form many of the different cell types found in the body.
… of the different cell types found in the body. When stem cells divide, they can form more stem cells or other cells that perform specialized functions. Embryonic stem …