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Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
… Sickle cell disease is a group of inherited red blood cell disorders. … Sickle cell disease is the most common inherited blood disorder in the United States. Approximately 100,000 … oxygen from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) are …
News Release
Researchers used whole genome sequence data to investigate the origin of the mutation that causes "sickling" of red blood cells.
… the origin of the mutation that causes sickling of red blood cells, which reduces their ability to carry oxygen and can … the origin of the mutation that causes "sickling" of red blood cells. ​ … the origin of the mutation that causes "sickling" of red blood cells. …
Fact Sheet
Learn about the different types of hemoglobin.
… disease and gene therapy , you should first know about blood cells and the different types of hemoglobin that make up red blood cells. … Hemoglobin types and sickle cell disease  Your red blood cells contain hemoglobin , a protein that carries … of blood cell in your body, such as white blood cells, red blood cells and platelets. Blood stem cells live and …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… After postdoctoral work at NIH's National Heart, Lung and Blood Institute, Dr. Bodine founded the Hematopoiesis Section … College in 2013 for his contributions to the genetics of blood disorders. As a graduate student, he was the recipient … National Disease Research Interchange and the Wisconsin Blood Center. Dr. Bodine is an active member of the American …
Educational Resources
A somatic cell is any cell of the body except sperm and egg cells.
… Somatic Cells … A somatic cell is any cell of the body except sperm and egg cells. … Somatic cells are the cells in the body other than sperm and egg cells (which are called germ cells). In humans, somatic cells … A somatic cell is any cell of the body except sperm and egg cells. …
Educational Resources
A cell cycle is a series of events that takes place in a cell as it grows and divides.
… mitosis, and completes its division. The resulting cells, known as daughter cells, each enter their own interphase and begin a new round …
Educational Resources
The cell membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside environment.
… membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside … Plasma Membrane, Proteins, Glycoproteins, Lipid Bilayer, Cells … membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside …
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… of Health (NIH) have discovered the genomic switches of a blood cell are key to regulating the human immune system. The … occur when the immune system mistakenly attacks its own cells, causing inflammation. Different tissues are affected … Dr. O'Shea's team began by searching for SEs in T cells, immune cells known to play an important role in …
News Release
NIH researchers and collaborators have found that that sickle cell trait is prevalent among diverse human populations.
… known as having sickle cell trait , increases the risk of blood clots, a risk that is the same among diverse human … sickle cell disease, a genetic condition that causes red blood cells to become rigid and sticky, which blocks blood flow. … carriers for sickle cell disease have higher risks of blood clots across diverse ancestries …
Educational Resources
A cell is the basic building block of living things.
… A cell is the basic building block of living things. All cells can be sorted into one of two groups: eukaryotes and … not. Plants and animals are made of numerous eukaryotic cells, while many microbes, such as bacteria, consist of single cells. An adult human body is estimated to contain between 10 …