The International Mouse Genome Sequencing Consortium (which was part of the Human Genome Project) completed a high-quality draft sequence of the mouse genome. The paper describing the mouse genome also compared it to a recently completed draft of the human genome. The mouse sequence is an important resource for unraveling the mysteries of the human genome. DNA sequences that have been conserved between the two are presumably functionally important. This means that mice can be used in laboratory experiments to investigate gene functions. The mouse data will allow researchers to explore how mouse genes and their human counterparts contribute to health and disease. Such research is expected to enhance the understanding of human disease and facilitate the development of new treatment options. As with the human genome sequence, the mouse data is freely available to researchers who can use it without restriction.
Waterson, R.H., Lindblad-Toh, K., Birney, E,. Rogers, J., et al. Initial sequencing and comparative analysis of the mouse genome. Nature, 420:520-562. 2002. [PubMed]
Last Reviewed: August 15, 2013