The PhenX Toolkit (https://www.phenxtoolkit.org/) is a freely available, web-based catalog of standard protocols for collecting data in biomedical and epidemiologic research. Studies that use PhenX (consensus measures for Phenotypes and eXposures) measures benefit from the ability to perform cross-study analyses to increase statistical power and to replicate results. The use of PhenX measures facilitates collaboration and data sharing, thus increasing the impact of individual studies.
Funded by the National Human Genome Research Institute of the National Institutes of Health (NIH), the PhenX Toolkit currently includes more than 500 measures from 24 research domains, with additional depth (measures) for substance abuse and addiction, mental health, tobacco regulatory, and sickle cell disease research. For each measure, the toolkit provides detailed instructions (e.g., required training and equipment); features (e.g., Spanish language versions); and bioinformatics support (e.g., data dictionaries, REDCap compatible modules) to facilitate implementation of the measures and data analysis downstream.
The PhenX Toolkit is widely used, with more than 2,500 registered users worldwide and an average of 755 visitors per day. PhenX measures have been recommended in more than 200 NIH funding opportunity announcements.
Erin M. Ramos, M.D., M.P.H.
Epidemiologist, Project Scientist
Scientific Program Analyst
Last Updated: October 24, 2017