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Peter J. McGuire, M.S., M.D.

Physician Scientist, Medical Genomics and Metabolic Genetics Branch
Immunometabolism Unit, Physician Scientist Development Program

Selected Publications

Offit, K., Gilewski, T., McGuire, P., Schluger, A., Hampel, H., Brown, K., Swenson, J., Neuhausen, S., Skolnick, M., Norton, L., and Goldgar, D. Germline BRCA1 185delAG mutations in Jewish women affected by breast cancer. Lancet, 347, 1643-1644. 1996. [PubMed]

Neuhausen, S., Gilewski, T., Norton, L., Tran, T., McGuire, P., Swensen, J., Hampel, H., Borgen, P., Brown, K., Skolnick, M., et al.  Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer. Nature Genetics, 13, 126-128. 1996. [PubMed]
Gurrieri, C., McGuire, P., Zan, H., Yan, X. J., Cerutti, A., Albesiano, E., Allen, S., Vinciguerra, V., Rai, K. R., Ferrarini, M., et al. Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intraclonal Ig VHDJH gene diversification. J Exp Med, 196, 629-639. 2002. [PubMed]
McGuire, P., Lim-Melia, E., Diaz, G.A., Raymond, K., Larkin, A., Shneider, B.L.,Wasserstein, M.P., Sansaricq, C. Combined liver-kidney transplant for the management of methylmalonic aciduria: a case report and review of the literature. Mol Genet Metab, 93: 22-29. 2008. [PubMed]
McGuire, P., Parikh, A., Diaz, G.A. Profiling of oxidative stress in patients with inborn errors of metabolism. Mol Genet Metab, 98:173-180. 2009. [PubMed]
Weisfeld-Adams, J.D.,  Morrissey, M.A., Kirmse, B.M., Salveson, B.R. Wasserstein, M.P.,   McGuire, P.J., Sunny, S., Cohen-Pfeffer, J.L., Yu, C., Caggana, M. Newborn screening and early biochemical follow-up in combined methylmalonic aciduria and homocystinuria, cblC type, and utility of methionine as a secondary screening analyte. Mol Genet Metab, 99:116-123. 2010. [PubMed]
McGuire, P.J., Cunningham-Rundles, C., Ochs, H., Diaz, G.A. Oligoclonality, impaired class switch and B cell memory responses in WHIM syndrome. Clin Immunol, 135:412-421. 2010. [PubMed]
McGuire, P.J., Lee, H.S., members of the Urea Cycle Disorders Consortium, Summar, M. Infectious precipitants of acute hyperammonemia are associated with indicators of increased morbidity in patients with urea cycle disorders. J Pediatr, 163:1705-1710. 2013. [PubMed]
Chandler, R. J., Tarasenko, T.N., Cusmano-Ozog, K., Sun, Q., Reid Sutton, V., Venditti, C.P., McGuire, P.J. Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model of citrullinemia type 1. Gene Ther, 20:1188-1191. 2013. [PubMed]
McGuire, P.J., Tarasenko, T.N., Wang, T., Levy, E., Zerfas, P.M., Moran, T.M., Lee, H.S., Bequette, B.J., Diaz, G.A. Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency. Dis Model Mech, 7:205-213. 2014. [PubMed]
Tan M., Peng C., Anderson K.A., Chhoy P., Xie Z., Dai L., Park J.S., Chen Y., Huang H., Zhang Y., Ro J., Wagner G.R., Green M.F., Madsen A.S., Schmiesing J., Peterson B.S., Xu G., Ilkayeva O.R., Muehlbauer M.J., Braulke T., Mühlhausen C., Backos D.S., Olsen C.A., McGuire P.J., Pletcher S.D., Lombard D.B., Hirschey M.D., Zhao Y. Lysine Glutarylation Is a Novel Protein Modification Regulated by SIRT5. Cell Metab, 19:605-617. 2014. [PubMed]

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Posted: November 25, 2014