The mission of the NIH Intramural Sequencing Center (NISC) is to produce high-quality DNA sequencing data with leading edge technologies to support investigator projects within the National Human Genome Research Institute (NHGRI) and across the NIH. NISC pursues increased operational efficiencies of high-throughput sequencing, refines existing protocols, implements additional protocols as new sample/experimental types are requested from researchers and continuously expands the value-added data analysis packages available to the research community. Furthermore, NISC monitors developments in rapidly evolving sequencing and informatics technologies, implementing those deemed most appropriate for NISC-generated sequence data produced for collaborating investigators.
Dr. James Thomas obtained his A.B. in biology from Washington University in St. Louis and completed his doctoral work in the Department of Genetics at Case Western Reserve University. In 1997, Dr. Thomas joined the NHGRI as a postdoctoral fellow and began his research in the emerging field of comparative genomics. Dr. Thomas went on to be an assistant professor in the Department of Human Genetics at the Emory University School of Medicine before returning to NHGRI and the NIH Intramural Sequencing Center in 2011. He is currently the deputy director of the NIH Intramural Sequencing Center.
As deputy director of NISC, Dr. Thomas evaluates and oversees implementation of new DNA sequencing technologies and protocols as well as efficiency and quality control related aspects of the data production pipeline. His research interests are in the field of comparative genomics and past projects have included genomic studies in a wide range of vertebrates.
Last Updated: November 1, 2016