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NIH

Meru J. Sadhu, Ph.D.

Investigator, Genetic Disease Research Branch
Head, Systems Biology and Genome Engineering Section

Sadhu MJ, Bloom JS, Day L, Siegel JJ, Kosuri S, Kruglyak L. Highly parallel genome variant engineering with CRISPR-Cas9. Nat Genet. 50(4):510-514. 2018.

Forsberg SK, Bloom JS, Sadhu MJ, Kruglyak L, Carlborg Ö. Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast. Nat Genet. 49(4):497-503. 2017. 

Sadhu MJ, Bloom JS, Day L, Kruglyak L. CRISPR-directed mitotic recombination enables genetic mapping without crosses. Science. 352(6289):1113-6. 2016.

Bloom JS, Kotenko I, Sadhu MJ, Treusch S, Albert FW, Kruglyak L. Genetic interactions contribute less than additive effects to quantitative trait variation in yeast. Nat Commun. 6:8712. 2015. 

Sadhu MJ, Moresco JJ, Zimmer AD, Yates JR 3rd, Rine J. Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae. Mol Biol Cell. 25(10):1653-65. 2015.

Sadhu MJ, Guan Q, Li F, Sales-Lee J, Iavarone AT, Hammond MC, Cande WZ, Rine J. Nutritional control of epigenetic processes in yeast and human cells. Genetics. 195(3):831-44. 2013.

Zill OA, Scannell DR, Kuei J, Sadhu M, Rine J. Evolutionary analysis of heterochromatin protein compatibility by interspecies complementation in Saccharomyces. Genetics. 192(3):1001-14. 2012. 

Nelson BR, Sadhu M, Kasemeier JC, Anderson LW, Lefcort F. Identification of genes regulating sensory neuron genesis and differentiation in the avian dorsal root ganglia. Dev Dyn. 229(3):618-29. 2004. 

Posted: October 29, 2018