Bioethics Core/Institutional Review Board
The Institutional Review Board (IRB) is responsible for protecting the rights and welfare of the human subjects of research protocols that are conducted by intramural investigators in NHGRI and a number of other institutes.
Oversight for human subjects research happening in the National Human Genome Research Institute (NHGRI) is provided by a centralized NIH Institutional Review Board Office (IRBO) located within the Office of Human Subjects Research Protections (OHSRP). The OHSRP promotes the protection of rights, safety and welfare of human subjects, and the NIH’s research mandate.
The NIH IRB meets daily to process actions submitted to the IRB via iRIS (a protocol management system). Please direct all your questions regarding IRB submissions to Brenton Yanos (NHGRI Protocol Navigator).
This page is intended to provide NHGRI Principal Investigators and research teams with quick access to the most relevant information and points of contact for the IRBO and NIH iRIS system.
National Institutes of Health (NIH)
- Office of Human Research Protections
- NIH Ethics Consult Service
- NIH Radiation Safety Committee (RSC)
- NIH Clinical Research Studies Active Consent / Assent Documents
- Recombinant DNA Advisory Committee (RAC)
- NIH Genomic Data Sharing
U.S. Federal Government
- 45 CFR 46 Federal Policy for the Protection of Human Subjects
- Office for Human Research Protections (OHRP)
- OHRP Approved Federal-Wide Assurances (FWAs)
- FDA Guidance for IRBs, Clinical Investigators and Sponsors
- FDA Investigator-Initiated Investigational New Drug (IND) Applications
- NHGRI Protocol Navigator
- NHGRI Bioethics Core
Last updated: July 7, 2021