Advancing Genomic Medicine Research (AGMR)

The AGMR program stimulates innovation and advance understanding of when, where and how best to implement the use of genomic information and technologies in clinical care.

Overview

Historically, NHGRI has largely funded genomic medicine research through multi-disciplinary consortia. The AGMR program expands NHGRI’s genomic medicine portfolio to include focused research projects that propose nimble, flexible approaches to problems in application or implementation of genomic medicine. AGMR investigators participate in at least one annual meeting, allowing for independent but synergistic efforts among grantees and promoting rapid sharing of successful approaches and resulting data.

Investigators

Names	Institution	Project Title
Pankaj B. Agrawal Margaret Graham Kemper Parker Timothy Wei-Wen Yu	Boston Children's Hospital	VIGOR: Virtual Genome Center for Infant Health
Lisa Bastarache Douglas Ruderfer	Vanderbilt University Medical Center	Translating the Clinical Knowledge of Mendelian Diseases to Real-World EHR Data to Improve Identification of Undiagnosed Patients
Hugo J. Bellen Michael Francis Wangler	Baylor College of Medicine	Genomic Medicine and Gene Function Implementation for an Underserved Population
Jonathan S. Berg Laura Vogel Milko	Univ of North Carolina Chapel Hill	Age-Based Genomic Screening in Newborns, Infants and Children: A Novel Paradigm in Public Health Genomics
Eric A. Boerwinkle Samden Lhatoo GQ Zhang	University of Texas Hlth Sci Ctr Houston	Implementation Science for Genomic Health Translation (INSIGHT)
Catherine Astrid Brownstein	Boston Children's Hospital	Navigating Online Patient Experiences of Genomic Medicine: Identifying and Overcoming Obstacles for African American Communities
Julio David Duarte	University of Florida	Preemptive Pharmacogenetic Testing in Medically Underserved Populations
Renata Constance Gallagher	University of California, San Francisco	Toward DNA Sequencing as a Primary Newborn Screen for Treatable Disorders Not Amenable to Current Screening
Cong Liu	Columbia University Health Sciences	RESCUE: Rare Disease Detection and Escalation Support Via a Learning Health System
Gabor T. Marth Martin Tristani-Firouzi	University of Utah	Calypso: A Web Software System Supporting Team-Based, Longitudinal Genomic Diagnostic Care
Katherine L. Nathanson Marylyn D. Ritchie Robert A. Schnoll	University of Pennsylvania	Using Behavioral Economics and Implementation Science to Advance the Use of Genomic Medicine Utilizing an EHR Infrastructure Across a Diverse Health System
Lori Ann Orlando	Duke University	Deploying a Genomic Medicine Risk Assessment Model for Diverse Primary Care Populations and Settings
Joseph F. Peterson Jing Hao David L. Veenstra	Vanderbilt University Medical Center	Rational Integration of Polygenic Risk Scores (RIPS)
Kathryn A. Phillips	University of California, San Francisco	Building the Evidence Base for Appropriate and Efficient Implementation of Emerging Genomic Tests for Disease Management and Screening
Marc S. Williams	Geisinger Clinic	Real-Time Genetic Diagnosis at the Point of Care

More information about AGMR’s funded projects is available in NIH’s RePORTER.

Funding Opportunities

RFA-HG-20-036: Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
Expiration Date: Mar 14, 2023
RFA-HG-20-037: Advancing Genomic Medicine Research (R21 Clinical Trial Optional)
Expiration Date: Mar 14, 2023

Program Staff

Program Directors

Christine Q. Chang, M.P.H.

Program Director
Division of Genomic Medicine

Renee Rider, M.S., J.D., LCGC

Program Director
Division of Genomic Medicine

Program Analysts

Jahnavi Narula, B.S.

Scientific Program Analyst
Division of Genomic Medicine

Last updated: October 27, 2022