2017 Advanced Genomic Technology Development Meeting

Event Details

The National Human Genome Research Institute (NHGRI) hosted the Advanced Genomic Technology Development Meeting at Northeastern University in Boston, Massachusetts, from May 22-25, 2017.

The meeting served as an open forum for NHGRI Genomic Technology Program grantees and other scientists and engineers to exchange knowledge and discuss key scientific and technical challenges. The purpose of facilitating these discussions is to advance a broad set of genomic technologies including those for nucleic acid sequencing.

to

Northeastern University
Boston, Massachusetts

Agenda

  • Monday, May 22, 2018

  • 4:00 p.m. Registration and Informal Poster Session
  • 5:20 p.m. Brief Introduction
    Mike Smith
  • 5:30 p.m. CMOS-integrated solid-state nanopore platform for high-bandwith DNA translocation measurements
    Ken Shepard
  • 6:00 p.m. Towards single molecule RNA sequencing using recognition tunneling
    Stuard Lindsay
  • 6:30 p.m. High-throughput genetic interaction sequencing in mammalian cells
  • Sasha Levy
  • 7:00 p.m. Towards single-molecule RNA sequencing by recognition tunneling
    Martha Bulyk
  • 7:30 p.m. Evening Snack and then adjourn for the day

 

  • Tuesday, May 23, 2018

  • 7:30 a.m. Breakfast and Registration
  • 8:10 a.m. Welcome
    Mike Smith and Carolyn Hutter
  • Session Chair: Meni Wanunu
  • 8:25 a.m. Achieving single nucleotide resolution to enable DNA flossing through alpha-hemolysin
    Anna Schibel
  • 8:55 a.m. Nanopore arrays with stabilized bilayers
    Reza Ghadiri
  • 9:25 a.m. Towards high accuracy nanopore sequencing
    Jens Gundlach
  • 9:55 a.m. BREAK
  • 10:20 a.m. Single-molecule electronic measurements of DNA polymerase I attached to carbon nanotube transistors
    Philip Collins
  • 10:50 a.m. Modeling macromolecular transport through protein channels and nanopores
    Murugappan Muthukumar
  • 11:20 a.m. Plasmonic nanopores for trapping, controlling displacement, and sequencing of DNA
    Aleksei Aksimentiev
  • 11:50 a.m. Direct picogram DNA and RNA sequencing using nanopore zero-mode waveguides
    Meni Wanunu
  • 12:20 p.m. Lunch and Poster Session I
    (Mon PM & Tues AM speakers and odd numbered poster presenters at boards 12:45-1:35pm)
  • Session Chair: Carolyn Hutter
  • 1:55 p.m. Sequencing by synthesis in nanogaps using water-soluble polymers as electrical tags
    Serge Lemay
  • 2:25 p.m. Multidimensional epigenomic single cell analysis
    Chongyuan Luo
  • 2:55 p.m. Cell type-specific mouse brain methylomes profiled using an ultralow-input microfluidic device
    Chang Lu
  • 3:25 p.m. DNA-microscopy
    Joshua Weinstein
  • 3:55 p.m. Group Photo and Break
  • 4:25 p.m. Poster Session II
    (Tues PM & Wed AM speakers and even numbered poster presenters at boards)
  • 5:15 p.m. Lead into discussion: Dreaming Big - What makes you think you can do that?
    Meni Wanunu
  • 5:35 p.m. Lead into discussion: Dreaming Big - What makes you think you can do that?
    John Nelson
  • 5:55 p.m. Discussion Q&A
  • 6:30 p.m. Northeastern Reception

 

  • Wednesday, May 24, 2018

  • CLOSED SESSION
  • 7:30 a.m. Breakfast
  • Session Chair: Serge Lemay
  • 8:15 a.m. Nanofluidic platforms for high resolution mapping of genomic DNA
    J. Michael Ramsey
  • 8:45 a.m. Technologies for complete human genome sequencing
  • Jeremy Edwards
  • 9:15 a.m. Allele-specific enrichment and depletion of nucleic acid variants
    David Yu Zhang
  • 9:45 a.m. Highly accurate genome sequencing of single cells with SISSOR
    Xiaohua Huang
  • 10:15 a.m. Single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array
    Carl Fuller
  • 10:45 a.m. BREAK
  • 11:20 a.m. Lead into Discussion: Where does technology need to go from here?
    Mark Akeson
  • 11:40 a.m. Lead into Discussion: Where does technology need to go from here?
    Chad Nusbaum
  • 12:00 p.m.

    Discussion Q&A and Working Lunch

  • 12:45 p.m. Break (Prepare for Open Meeting)
  • OPEN SESSION
  • 1:45 p.m. Welcome/Overview
    Mike Smith and Carolyn Hutter
  • 2:00 p.m. Lead into Discussion: Defining and staying on the cutting edge
    David Page
  • 2:20 p.m. Lead into Discussion: Defining and staying on the cutting edge
    George Church
  • 2:40 p.m. Lead into Discussion: Defining and staying on the cutting edge
    Joe Beechem
  • 3:00 p.m. Discussion Q&A
  • 3:45 p.m. BREAK
  • 4:00 p.m. Recent progress on nanopore sequencing at UC Santa Cruz
    Mark Akeson
  • 4:30 p.m. Library-free, targeted sequencing of native gDNA from FFPE samples using Hyb & SeqTM technology - the hybridization based single molecule sequencing system
    Joe Beechem
  • 5:00 p.m. Bacterial methylomes
    Rich Roberts
  • 6:15 p.m. Northeastern Reception
  • 8:00 p.m. Adjourn for the Day

 

  • Thursday, May 25, 2018

  • 7:30 a.m. Breakfast
  • Session Chair: Mike Smith
  • 8:30 a.m. Nanopore enabled exonuclease sequencing
    Eric Ervin
  • 9:00 a.m. High Content Pooled Genomic Sequencing
    Paul Blainey
  • 9:30 a.m. Detecting nucleotide modifications using nanopores sequencing
    Winston Timp
  • 10:00 a.m. Poster Session III (public meeting speakers at posters)
  • 10:45 a.m. Unlocking the combinatorial epigenetic code at a single-molecule level
    Efrat Shema
  • 11:15 a.m. Expanding the scope of genetic screens using single-cell genomics
    Andrew Hill
  • 11:45 a.m. Producing finished quality sequence of structurally complex genomic regions with SHIMS 2.0
    Daniel Bellott
  • 12:15 p.m. Break and grab lunch for working meal
  • 12:30 p.m. Renaissance in antibiotic discovery
    Slava Epstein
  • 1:00 p.m. Nanopore-based characterization of pyrimidine-tagged RNAs
    Anastassia Kanavarioti
  • 1:30 p.m. Closing Discussion
  • 1:45 p.m. Meeting Adjourns

Last updated: August 6, 2018