Gene-Environment Interplay in Common Complex Diseases: Forging an Integrative Model

8:00 a.m.

Registration

8:30 a.m.

Welcome and Introduction
Deborah H. Olster, Ph.D., Deputy Director, OBSSR
Eric Green, M.D., Ph.D., Director, NHGRI
Linda S. Birnbaum, Ph.D., DABT, ATS, Director, NIEHS

9:00 a.m.

Symposium Summary:  New Models for Large Prospective Studies
Teri Manolio, M.D., Ph.D., NHGRI

9:15 a.m.

10:15 a.m.

Break

10:30 a.m.

GxE Interplay: The perspective from the environment side

Molecular Exposures
Frederica P. Perera, MPH, DrPH, Columbia University

Developmental Psychology
Eric Turkheimer, Ph.D., University of Virginia

Social Science
Jason D. Boardman, Ph.D., University of Colorado at Boulder

11:30 a.m.

Overview of afternoon and goals for breakout sessions

12:00 p.m.

Lunch (on your own)

1:00 p.m.

Breakout Group Discussions in Natcher Meeting Rooms
Breakout Groups and  Leaders

Theory and Study Design A
Mary L. Marazita, Ph.D., FACMG,  University of Pittsburgh
Stephen M. Rappaport, Ph.D.,  University of California, Berkeley

Theory and Study Design B
Eric Boerwinkle, Ph.D., The University of Texas
Stephen J. Suomi, Ph.D., Eunice Kennedy Shriver National Institute of Child Health and Human Development

Methods and Analysis A
Neil E. Caporaso, M.D.,  National Cancer Institute
Irva Hertz-Picciotto, Ph.D., MPH,  University of California, Davis

Methods and Analysis B
Nancy J. Cox, Ph.D.,  The University of Chicago
Kristen C. Jacobson, Ph.D.,  The University of Chicago

Phenotypes, Endophenotypes and Variables A
William L. Lowe, Jr., M.D., Northwestern University
Lynn R. Goldman, M.D., MPH, Johns Hopkins University

Phenotypes, Endophenotypes and Variables B
Priya Duggal, Ph.D., MPH, Johns Hopkins University
Megan R. Gunnar, Ph.D.,  University of Minnesota

3:00 p.m.

Break

3:15 p.m.

Reports from the Break Out Group Leaders (10 minute presentations in Natcher Auditorium)

4:15 p.m.

Panel Discussion and Q&A

5:00 p.m.

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