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Generic Bases

Genomic Variation

updated: July 25, 2024


Genomic variation refers to DNA sequence differences among individuals or populations. Some variants influence biological function (such as a mutation that causes a genetic disease), while others have no biological effects.


Genomic Variation. By understanding genomic variation in families, in populations, we can know how our genetic makeup varies between us individuals. It may help us to understand why even within families people have different blood groups and eye colors. Genomic variation may also be the reason why some populations or persons within a certain population may have higher risk of certain diseases compared to others.

Charles Rotimi
Charles Rotimi, Ph.D.

Scientific Director

Division of Intramural Research