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​LOD Score

updated: April 16, 2024


An LOD (short for “logarithm of the odds”) score is a statistical estimate of the relative probability that two loci (e.g., a disease-associated gene and another sequence of interest, such as a variant or another gene) are located near each other on a chromosome and are therefore likely to be inherited together.


LOD Score. We use LOD scores when we're mapping the relationship of genes genetically from one to another.

Lawrence Brody
Lawrence Brody, Ph.D.


Division of Genomics and Society