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​LOD Score

updated: May 10, 2022

Definition

An LOD (short for “logarithm of the odds”) score is a statistical estimate of the relative probability that two loci (e.g., a disease-associated gene and another sequence of interest, such as a variant or another gene) are located near each other on a chromosome and are therefore likely to be inherited together.



Narration

LOD Score. We use LOD scores when we're mapping the relationship of genes genetically from one to another.

Lawrence Brody
Lawrence Brody, Ph.D.

Director

Division of Genomics and Society