Skip Navigation
NIH

Talking Glossary of Genetic Terms

Listen to Definition

Fabio Candotti, M.D. defines Gene Expression

Gene Expression

Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule. The cell reads the sequence of the gene in groups of three bases. Each group of three bases (codon) corresponds to one of 20 different amino acids used to build the protein.

How to cite this term How to cite this term for research papers


A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Gene Expression

Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule. The cell reads the sequence of the gene in groups of three bases. Each group of three bases (codon) corresponds to one of 20 different amino acids used to build the protein.

Narration Transcription

Gene expression is the process the cell uses to produce the molecule it needs by reading the genetic code written in the DNA. To do this, the cell interprets the genetic code, and for each group of three letters it adds one of the 20 different amino acids that are the basic units needed to build proteins.


Doctor Profile

Fabio Candotti, M.D.

Fabio Candotti, M.D.

Occupation
Senior Investigator, Genetics and Molecular Biology Branch; Head, Disorders of Immunity Section

Biography
Dr. Candotti's laboratory studies the molecular basis of inherited disorders of the immune system in order to develop better treatments for these conditions. Currently, for many inherited immune deficiency disorders, the only available therapeutic option is hematopoietic stem cell transplantation (HSCT), an intensive procedure that carries a number of risks. Dr. Candotti is seeking treatment alternatives to HSCT, focusing on gene replacement approaches. His laboratory is developing gene therapies for two rare immune deficiency syndromes, adenosine deaminase (ADA) deficiency and Wiskott-Aldrich syndrome (WAS).

How to cite this termHow to cite this term for research papers

Illustrations

Advanced Illustrations

About the Talking Glossary
all Top