Research Funding Opportunities

To apprise the community of research areas that support that mission, NHGRI periodically publishes funding opportunities in the NIH Guide for Grants and Contracts. For your convenience, we have also listed the funding opportunities related to NHGRI on this webpage. NHGRI welcomes innovative investigator-initiated applications and encourages investigators with novel ideas to discuss potential applications with program staff during the concept development stage of the application. If you are considering applying for a Program Announcement with special review (PAR) , a Request for Applications (RFA), or an application that exceeds $500K in direct cost in any one year, we encourage you to review the Guidance to Potential Applicants for NHGRI Support.

For how NHGRI will treat new and non-competing applications, see the FY2020 Funding Policy.

• Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression Project (U24 Clinical Trial Not Allowed)
  RFA-HG-20-039
  Application Due Date(s): November 13, 2020
  Expiration Date: November 14, 2020

• Advancing Genomic Medicine Research (Clinical Trial Optional) (R01)
  RFA-HG-20-036
  Due Dates: August 3, 2020; March 8, 2021; November 2, 2021; August 1, 2022; March 13, 2023
  Expiration Date: March 14, 2023

• Advancing Genomic Medicine Research (Clinical Trial Optional) (R21)
  RFA-HG-20-037
  Due Dates: August 3, 2020; March 8, 2021; November 2, 2021; August 1, 2022; March 13, 2023
  Expiration Date: March 14, 2023

• Rescinding NOT-HG-20-041 “NHGRI Late Application Policy for NHGRI-Specific FOAs with Application Due Dates in May, June, and July” and Clarifying the Late Application Receipt Dates of NHGRI-Specific FOAs
  NOT-HG-20-042
   
• Genomic Community Resources (U24)
  PAR-20-100
  Application Due Date(s): First due date is May 25, 2020; Standard dates apply after that, by 5:00 PM local time of applicant organization.
  Expiration Date: January 26, 2023
   
• Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites (U01 Clinical Trial Not Allowed)
  RFA-HG-20-001
  Application Due Date(s): June 23, 2020
  Expiration Date: June 24, 2020
  
  Pre-Application Webinar for RFA-HG-20-001 and RFA-HG-20-002, Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites and Coordinating Center (U01 Clinical Trial Not Allowed)
  NOT-HG-20-038
   
• Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Coordinating Center (U01 Clinical Trial Not Allowed)
  RFA-HG-20-002
  Application Due Date(s): June 23, 2020
  Expiration Date: June 24, 2020
   
• Novel Synthetic Nucleic Acid Technology Development (R01 Clinical Trial not allowed)
  RFA-HG-20-014
  Application Due Date(s): June 24, 2020; February 1, 2021; October 1, 2021; June 24, 2022
  Expiration Date: June 25, 2022
   
• Novel Synthetic Nucleic Acid Technology Development (R21) (Clinical Trial not allowed)
  RFA-HG-20-015
  Application Due Date(s): June 24, 2020; February 1, 2021; October 1, 2021; June 24, 2022
  Expiration Date: June 25, 2022
   
• Novel Synthetic Nucleic Acid Technology Development (R43/R44) (Clinical Trial Not Allowed)
  RFA-HG-20-016
  Application Due Date(s): June 24, 2020; February 1, 2021; October 1, 2021; June 24, 2022
  Expiration Date: June 25, 2022
   
• NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed)
  RFA-HG-20-019
  Application Due Date(s): June 24, 2020
  Expiration Date: June 25, 2020
   
• Notice of Special Interest: Genomic Data Repositories (PAR-20-089) and Knowledgebases (PAR-20-097)
  NOT-HG-20-017
   
• Mendelian Genomics Research Centers (U01 - Clinical Trial Optional)
  RFA-HG-20-007
  Application Due Date(s): July 15, 2020
  Expiration Date: July 16, 2020
   
• Mendelian Genomics Data Coordinating Center (U24 Clinical Trial Not Allowed)
  RFA-HG-20-008
  Application Due Date(s): July 15, 2020
  Expiration Date: July 16, 2020
   
• Notice of Special Interest: Development of Statistical, Population Genetics and Computational Methods Related to Polygenic Prediction of Health and Disease in Diverse Populations
  NOT-HG-20-010
   
• Notice of Change: Emphasizing an Opportunity for New Institutional Applicants in Response to PAR-19-204 Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
  NOT-HG-20-013
   
• NHGRI Implementation of the NIH Genomic Data Sharing Policy
  NOT-HG-20-011
   
• Notice of Intent to Publish Funding Opportunity Announcements for Mendelian Genomics Research Consortium
  NOT-HG-20-009
   
• Notice of New NIH-Designated Data Repository: NHGRI’s Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)
  NOT-HG-19-024
   
• Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
  PAR-19-204
  Application Due Date(s): May 20, 2019; May 18, 2020; May 20, 2021
  Expiration Date: May 21, 2021
   
• Investigator-Initiated Genomic Medicine Research (R01 Clinical Trial Optional)
  PAR-18-735
  Application Due Date(s): June 20, 2018; October 19, 2018; June 20, 2019; October 21, 2019; June 19, 2020; October 20, 2020
  Expiration Date: January 23, 2021
  
  Notice of Early Expiration of PAR-18-735 (Investigator-Initiated Genomic Medicine Research (R01 Clinical Trial Optional) and PAR-18-736 (Investigator-Initiated Genomic Medicine Research (R21 Clinical Trial Optional)
  NOT-HG-20-051
   
• Investigator-Initiated Genomic Medicine Research (R21 Clinical Trial Optional)
  PAR-18-736
  Application Due Date(s): June 20, 2018; October 19, 2018; June 20, 2019; October 21, 2019; June 19, 2020; October 20, 2020
  Expiration Date: January 23, 2021
  
  Notice of Early Expiration of PAR-18-735 (Investigator-Initiated Genomic Medicine Research (R01 Clinical Trial Optional) and PAR-18-736 (Investigator-Initiated Genomic Medicine Research (R21 Clinical Trial Optional)
  NOT-HG-20-051
  ​​​​​​​
• Genomic Innovator Award (R35 Clinical Trial Optional) 
  RFA-HG-18-006 
  Application Due Dates: October 30, 2018; October 30, 2019; October 30, 2020
  Expiration Date: October 31, 2020
   
• Novel Approaches for Relating Genetic Variation to Function and Disease (R21 Clinical Trial Not Allowed) 
  PAR-18-867
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: July 17, 2021
   
• Novel Approaches for Relating Genetic Variation to Function and Disease (R01 Clinical Trial Not Allowed) 
  PAR-18-868
  Application Due Dates: February 5, June 5, October 5
  Expiration Date: July 6, 2021
   
• Investigator Initiated Research in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed) 
  PAR-18-843 
  Application Due Date(s): November 16, 2018; July 16, 2019; November 16, 2019; July 16, 2020; November 16, 2020; July 16, 2021?
  Expiration Date: September 8, 2021
   
• Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)  
  PAR-18-844
  Application Due Date(s): November 16, 2018; July 16, 2019; November 16, 2019; July 16, 2020; November 16, 2020; July 16, 2021
  Expiration Date: September 8, 2021
   
• Novel Genomic Technology Development (R01 Clinical Trial Not Allowed) 
  PAR-18-777 
  Application Due Date(s): October 2, 2018; October 2, 2019; October 2, 2020
  Expiration Date: January 8, 2021

• Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed) 
  PAR-18-779  
  Application Due Date(s): October 2, 2018; October 2, 2019; October 2, 2020
  Expiration Date: January 8, 2021

• Novel Genomic Technology Development (R21 Clinical Trial Not Allowed) 
  PAR-18-778
  Application Due Date(s): October 2, 2018; October 2, 2019; October 2, 2020
  Expiration Date: January 8, 2021

• Novel Nucleic Acid Sequencing Technology Development (R01 Clinical Trial Not Allowed)
  RFA-HG-18-001
  Application Due Date(s): June 27, 2018; June 27, 2019; June 26, 2020
  Expiration Date: September 11, 2020

• Novel Nucleic Acid Sequencing Technology Development (R21 Clinical Trial Not Allowed)
  RFA-HG-18-002 
  Application Due Date(s): June 27, 2018; June 27, 2019; June 26, 2020
  Expiration Date: September 11, 2020

• Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed)
  RFA-HG-18-003 
  Application Due Date(s): June 27, 2018; June 27, 2019; June 26, 2020
  Expiration Date: September 11, 2020

• Comparative Genomics Research Program (R01-Clinical Trial Not Allowed)
  PAR-17-482 
  Application Due Date(s): February 5, June 5, October 5
  Expiration Date: January 8, 2021
   
  • Notice of U.S. Department of Agriculture (USDA) Participation in PAR-17-482 "Comparative Genomics Research Program (R01) 
    NOT-HG-18-007 
     
  • Frequently Asked Questions: PAR-18-482 Comparative Genomics Research Program 
     
• Ethical, Legal, and Social Implications (ELSI) of Genomic Research Regular Research Program (R01) 
  PA-17-325 
  Application Receipt Date(s): Standard dates apply
  Expiration Date: September 8, 2020
   
• Ethical, Legal, and Social Implications (ELSI) of Genomic Research Small Research Grant Program (R03) 
  PA-17-324 
  Application Receipt Date(s): Standard dates apply
  Expiration Date: September 8, 2020
   
• Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Grant Program (R21) 
  PA-17-323 
  Application Receipt Date(s): Standard dates apply
  Expiration Date: September 8, 2020
   
• Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01)
  PAR-17-269 
  Application Due Date(s): Applications are accepted by continuous receipt by 5:00 PM local time of applicant organization.
  Expiration Date: July 11, 2020

• NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required)
  PA-20-194
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: May 8, 2023
   
• NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)
  PA-20-195
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: May 8, 2023
   
• NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
  PA-19-056
  Application Receipt Date(s): February 5, June 5, October 5
  Expiration Date: January 8, 2022
   
• Research Project Grant (Parent R01 Clinical Trial Required)
  PA-19-055
  Application Receipt Date(s): February 5, June 5, October 5
  Expiration Date: January 8, 2022
   
• SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, R44) Clinical Trial Not Allowed
  PAR-19-334
   
• Notice of Special Interest: Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Applications Directed at the Adoption of the Fast Healthcare Interoperability Resources (FHIR®) Standard
  NOT-OD-19-127
   
• Change of Grantee Organization (Type 7 Parent Clinical Trial Optional)
  PA-18-590 
  Application Receipt Date(s): A change of grantee organization request must be made before the anticipated start date at the new organization and preferably several months in advance.
  Expiration Date: January 26, 2021
   
• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
  PA-18-589 
  Application Receipt Date(s): A change of grantee organization request must be made before the anticipated start date at the new organization and preferably several months in advance.
  Expiration Date: January 26, 2021
   
• PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
  PA-19-272
   
• PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
  PA-19-273
   
• PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
  PA-19-270
   
• PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
  PA-19-271 
   
• NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
  PA-19-052

• NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) 
  PA-18-648 
  Application Due Date(s): April 12, August 12, December 12
  Expiration Date: January 8, 2021

• Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Admin Supp)
  PA-18-591 
  Application Receipt Date(s): Multiple dates, see announcement.
  Expiration Date: January 26, 2021
  
  Administrative Supplements - NHGRI Guidance

• Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed)
  PA-18-504 
  Application Due Date(s): February 25, June 25, October 25
  Expiration Date: January 8, 2021
• NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required) 
  PA-18-344 
  Application Receipt Date(s): February 16, June 16, October 16
  Expiration Date: January 8, 2021
   
  • Companion Funding Opportunity:
    PA-18-489 - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)
     
• Research on the Health of Transgender and Gender Nonconforming Populations (R21) 
  PA-17-477 
  Application Receipt Date(s): February 16, June 16, October 16
  Expiration Date: September 8, 2020
   
• Research on the Health of Transgender and Gender Nonconforming Populations (R01) 
  PA-17-478 
  Application Receipt Date(s): February 5, June 5, October 5
  Expiration Date: September 8, 2020
   

• Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions and Administrative Supplements for Research on Coronavirus Disease 2019 (COVID-19) in Individuals with Down Syndrome for the INCLUDE Project
  NOT-OD-20-129

• Notice of Common Funds Participation in PA-20-135 "Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)"
  NOT-RM-20-016

• Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional)
  PAR-20-167
  Application Due Date(s): August 28, 2020
  Expiration Date: August 29, 2020

• Genomic Predictors of Pregnancy Loss (R01 Clinical Trial Not Allowed)
  RFA-HD-21-005
  Application Due Date(s): July 30, 2020
  Expiration Date: July 31, 2020

• Notice of Special Interest: Notice of Administrative Supplements for Stakeholder Engagement in Genomic Medicine Research
  NOT-HG-20-031

• Notice of NHGRI’s Participation in PA-18-935 "Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional)"
  NOT-HG-20-034

• Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions for Research on the 2019 Novel Coronavirus
  NOT-HG-20-030

• Notice of Special Interest (NOSI): Availability of Administrative Supplements to Advance Safe and Effective Therapeutics in Pregnant and Lactating Women and Children
  NOT-HD-20-003

• Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)
  PA-20-135
  Application Due Date(s): See the Emergency Notice of Special Interest (NOSI) for any applicable Application Due Dates.
  Expiration Date: March 10, 2023

• Notice of Special Interest (NOSI): Administrative Supplements to Support Enhancement of Software Tools for Open Science
  NOT-OD-20-073

• Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed)
  PA-20-025
  Application Due Date(s): September 5, January 5, April 5
  Expiration Date: January 6, 2023

• Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed)
  PA-20-047
  Application Due Date(s): September 5, January 5, April 5
  Expiration Date: January 6, 2023

• Notice of Special Interest: Administrative Supplement for Research on Bioethical Issues (Admin Supp Clinical Trial Optional)
  NOT-OD-20-038

• Notice of Special Interest: Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars
  NOT-OD-20-054

• Notice of Special Interest: Alzheimers-focused administrative supplements for NIH grants that are not focused on Alzheimers disease
  NOT-AG-20-008

• Notice of Special Interest: Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp Clinical Trial Optional)
  NOT-OD-20-032

• Notice of Special Interest (NOSI): Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship Awards to Support Training in Research Related to Down Syndrome as Part of the INCLUDE Project
  NOT-OD-20-020

• Notice of Special Interest (NOSI): Mentored Career Development Awards to Foster the Careers of Investigators Pursuing Research Related to Down syndrome as Part of the INCLUDE Project
  NOT-OD-20-021

• Notice of Special Interest: Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional)
  NOT-OD-20-048

• Notice of Special Interest: Administrative Supplements for Research on Sex/Gender Influences (Admin Supp Clinical Trial Optional)
  NOT-OD-20-049

• Notice of NHGRI Participation in PAR-19-372, Social Epigenomics Research Focused on Minority Health and Health Disparities (R01-Clinical Trial Not Allowed)
  NOT-HG-19-026

• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
  PAR-19-274
  Application Receipt/Submission Date(s): February 5, June 5, October 5
  Expiration Date: May 8, 2022

• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
  PAR-19-275
  Application Receipt/Submission Date(s): February 16, June 16, October 16
  Expiration Date: May 8, 2022

• Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
  PAR-19-276
  Application Receipt/Submission Date(s): February 16, June 16, October 16
  Expiration Date: May 8, 2022

• International Bioethics Research Training Program (D43 Clinical Trial Optional)
  PAR-19-243
  Application Receipt/Submission Date(s): June 4, 2019; June 4, 2020, June 4, 2021
  Expiration Date: June 5, 2021

• International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)
  PAR-19-244
  Application Receipt/Submission Date(s): June 4, 2019, June 4, 2020, June 4, 2021
  Expiration Date: June 5, 2021

• NIH Highlights Support for Data Science Research through the Academic Research Enhancement Award (AREA) Program
  NOT-GM-19-021 
   
• Notice of Special Interest in Research on the Health of Sexual and Gender Minority (SGM) Populations
  NOT-MD-19-001 
   
• National Science Foundation - National Institutes of Health NSF-NIH Interagency Initiative: Smart and Connected Health
  NOT-OD-18-149 

• Academic Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 - Clinical Trial Not Allowed) 
  PAR-18-714 
  Application Due Date: February 25, June 25, October 25
  Expiration Date: May 8, 2021

• Research on the Health of Transgender and Gender Nonconforming Populations (R21 Clinical Trial Optional) 
  PA-18-728 
  Application Due Date(s): February 16, June 16, October 16
  Expiration Date: January 8, 2021 
   
• Research on the Health of Transgender and Gender Nonconforming Populations (R01 Clinical Trial Optional) 
  PA-18-729 
  Application Due Date(s): February 5, June 5, October 5
  Expiration Date: January 8, 2021 
   
• National Science Foundation - National Institutes of Health NSF-NIH Interagency Initiative: Smart and Connected Health 
  NOT-OD-18-149 
   
• Announcing the High-Priority, Short-Term Project Award (R56) 
  • Notice of NHGRI's Participation in NOT-OD-04-047 "High Priority, Short-Term Project Award (R56)" 
    NOT-HG-17-004 [grants.nih.gov]