Research Funding Opportunities

To apprise the community of research areas that support that mission, NHGRI periodically publishes funding opportunities in the NIH Guide for Grants and Contracts. For your convenience, we have also listed the funding opportunities related to NHGRI on this webpage. NHGRI welcomes innovative investigator-initiated applications and encourages investigators with novel ideas to discuss potential applications with program staff during the concept development stage of the application. If you are considering applying for a Program Announcement with special review (PAR) , a Request for Applications (RFA), or an application that exceeds $500K in direct cost in any one year, we encourage you to review the Guidance to Potential Applicants for NHGRI Support.

For how NHGRI will treat new and non-competing applications, see the FY2022 Funding Policy.

• RFA-HG-23-041: Network of Genomics-Enabled Learning Health Systems (gLHS) – Clinical Sites (U01 Clinical Trial Required)
  Application Due Date(s): November 7, 2023
  Expiration Date: November 8, 2023
   
• RFA-HG-23-042: Network of Genomics-Enabled Learning Health Systems (gLHS) – Coordinating Center (U01 Clinical Trials Required)
  Application Due Date(s): November 7, 2023
  Expiration Date: November 8, 2023
   
• RFA-HG-23-027: Center for ELSI Resources and Analysis (U24 Clinical Trial Not Allowed)
  Application Due Date(s): October 26, 2023
  Expiration Date: October 27, 2023
   
• RFA-HG-23-024: Limited Competition: High Quality Reference Genomes (UM1 Clinical Trial Not Allowed)
  Application Due Date(s): August 15, 2023
  Expiration Date: August 16, 2023
   
• RFA-HG-23-017: Investigator-Initiated Research in Genomics and Health Equity (R01 Clinical Trial Optional)
  Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal)
  Expiration Date: July 09, 2025
   
• RFA-HG-23-018: Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional)
  Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal)
  Expiration Date: July 09, 2025
  
  NOT-HG-23-049: Notice of Pre-Application Webinar for the Investigator-Initiated Research in Genomics and Health Equity: RFA-HG-23-017 (R01 Clinical Trial Optional) and RFA-HG-23-018 (R21 Clinical Trial Optional)
• PAR-23-184: Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
  Application Due Dates: Applications are accepted by continuous receipt and are due by 5:00 PM local time of applicant organization. 
  Expiration Date: July 09, 2026
   
• PAR-20-254: Ethical, Legal and Social Implications (ELSI) (Research R01 Clinical Trial Optional)
  Application Due Dates: October 19, 2020, February 17, 2021, June 17, 2021, October 19, 2021, February 17, 2022, June 17, 2022, October 19, 2022, February 17, 2023, June 19, 2023, October 19, 2023.
  Expiration Date: November 18, 2023
  
  NOT-HG-23-036: Notice to Extend the Expiration Date of PAR-20-254: Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21) Clinical Trial Optional)
  
   
• PAR-20-255: Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
  Application Due Dates: October 19, 2020, February 17, 2021, June 17, 2021, October 19, 2021, February 17, 2022, June 17, 2022, October 19, 2022, February 17, 2023, June 19, 2023
  Expiration Date: July 20, 2023
  
  NOT-HG-23-037: Notice to Extend the Expiration Date of PAR-20-255: Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
   
• PAR-20-257: Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03) Clinical Trial Optional)
  October 19 2020, February 17 2021, June 17 2021, October 19 2021, February 17 2022, June 17 2022, October 19 2022, February 17 2023, June 19 2023, October 19, 2023
  Expiration Date: November 18, 2023
  
  NOT-HG-23-038: Notice to Extend the Expiration Date of PAR-20-257: Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)

• RFA-HG-23-005: Data Integration and Statistical Analysis Methods (DISAM) (U01 Clinical Trial Not Allowed)
  Application Due Date: November 20, 2023
  Expiration Date: November 21, 2023

• PAR-23-098: Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
  Application Due Date: June 23, 2023, June 21, 2024
  Expiration Date: June 22, 2024

• NOT-HG-23-035: Notice of Intent to Publish a Notice of Funding Opportunity for Advancing Genomic Medicine Research (R21 Clinical Trial Optional)

• NOT-HG-23-028: Notice of Intent to Publish a Funding Opportunity Announcement for Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed)

• RFA-HG-22-026: Diversity Centers for Genome Research (U54 Clinical Trials Optional)
  Application Due Dates: December 6, 2022; June 23, 2023; June 24, 2024
  Expiration Date: June 25, 2024

• NOT-HG-23-015: Notice of Change in Application and Submission Information-Page Limitations to RFA-HG-22-026: Diversity Centers for Genome Research (U54 Clinical Trials Optional)

• RFA-HG-22-027: Diversity Centers for Genome Research (UG3/UH3 Clinical Trials Optional)
  Application Due Dates: December 6, 2022; June 23, 2023; June 24, 2024
  Expiration Date: June 25, 2024

• Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
  PAR-22-107
  Application Receipt Date(s): June 21, 2024
  Expiration Date: June 22, 2024

• Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients’ Use of Genomic Information
  NOT-HG-22-011

• Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
  RFA-HG-22-001
  Application Due Dates: March 04, 2022, February 28, 2023, February 27, 2024
  Expiration Date: February 28, 2024

• New Investigators to Promote Workforce Diversity in Genomics, Bioinformatics, or Bioengineering and Biomedical Imaging Research (R01 Clinical Trial Optional)
  RFA-HG-21-041
  Application Due Dates: February 22, 2022; February 22, 2023; February 22, 2024 
  Expiration Date: February 23, 2024 

• Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
  PAR-21-254
  Application Due Dates: February 5, June 5, October 5
  Expiration Date: September 8, 2024

• Investigator Initiated Research in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed)
  PAR-21-255
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: September 8, 2024

• Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application
  NOT-HG-21-018

• Notice of Special Interest (NOSI): High-throughput Molecular and Cellular Phenotyping
  NOT-HG-21-004

• Notice of Special Interest: Genomic Data Repositories (PAR-20-089) and Knowledgebases (PAR-20-097)
  NOT-HG-20-017
   
• Notice of Special Interest: Development of Statistical, Population Genetics and Computational Methods Related to Polygenic Prediction of Health and Disease in Diverse Populations
  NOT-HG-20-010
   
• NHGRI Implementation of the NIH Genomic Data Sharing Policy
  NOT-HG-20-011
   
• Notice of New NIH-Designated Data Repository: NHGRI’s Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)
  NOT-HG-19-02

• Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Admin Supp)
  PA-20-272 
  Application Receipt Date(s): Multiple dates, see announcement.
  Expiration Date: July 24, 2023
• NOT-AG-23-015: Notice of Special Interest (NOSI): Alzheimer’s-Focused Administrative Supplements for NIH Grants that are Not Focused on Alzheimer’s Disease
  
  Guidance for NHGRI Grantees Requesting Administrative Supplements
• NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional)
  RFA-RM-23-005
  Application Due Date: August 18, 2023
  Expiration Date: August 19, 2023
• NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional)
  RFA-RM-23-004
  Application Receipt Date(s): September 8, 2023
  Expiration Date: September 9, 2023
• Research Project Grant (Parent R01 Clinical Trial Required)
  PA-20-183
  Expiration Date: May 8, 2023
• NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
  PA-20-185
  Expiration Date: May 8, 2023
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)
  PAR-21-357
  Expiration Date: January 8, 2025

• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
  PAR-22-060
  Expiration Date: January 8, 2025

• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
  PA-21-268 
  Expiration Date: June 30, 2024
   
• NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
  PA-21-151
  Application Receipt Date(s): Multiple dates, see announcement.
  Expiration Date: January 8, 2024
  
  Plans to Promote Safe Environments at Conferences Supported by NIH Grants and Cooperative Agreements
  NOT-OD-22-074
   
• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
  PA-20-275 
  Application Receipt Date(s): A change of grantee organization request must be made before the anticipated start date at the new organization and preferably several months in advance.
  Expiration Date: July 24, 2023
   
• NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required)
  PA-20-194
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: May 8, 2023
   
• NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)
  PA-20-195
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: May 8, 2023
   
• Change of Grantee Organization (Type 7 Parent Clinical Trial Optional)
  PA-18-590 
  Application Receipt Date(s): A change of grantee organization request must be made before the anticipated start date at the new organization and preferably several months in advance.
  Expiration Date: January 26, 2021
   
• NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
  PA-19-052

• NOT-TR-23-026: Notice of Special Interest (NOSI): Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3) (Clinical Trial Optional) for Advancing Recruitment through Trial Innovation Network (AR-TIN)

• PAR-23-124: Genomic Community Resources (U24 Clinical Trial Not Allowed)
  Application Due Date(s): May 25, 2023, September 25, 2023, January 25, 2024, September 25, 2024, January 25, 2025, September 25, 2025, January 25, 2026
  Expiration Date: January 26, 2026

• PAR-23-219: PAR-SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)
  Application Due Date(s): September 5, 2023, January 5, 2024, April 5, 2024, September 5, 2024, January 5, 2025, April 5, 2025
  Expiration Date: April 6, 2024

• PAR-23-220: SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1 Clinical Trial Required)
  Application Due Date(s): September 5, 2023, January 5, 2024, April 5, 2024, September 5, 2024, January 5, 2025, April 5, 2025
  Expiration Date: April 6, 2024

• NOT-AG-23-032: Notice of Special Interest (NOSI): Administrative Supplement Program to Help Develop Alzheimer’s-Focused NIH Grants

• PAR-23-166: Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
  Application Due Date(s): July 08, 2024, July 08, 2025, July 08, 2026
  Expiration Date: August 08, 2026

• PAR-23-156: Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional)
  Application Due Date(s): August 25, 2023
  Expiration Date: August 26, 2023

• NOT-OD-23-106: Revising the NIH/AHRQ/NIOSH Post-Submission Material Policy

• PAR-23-138: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

• NOT-OD-23-073: Notice of Special Interest (NOSI): Administrative Supplements to Enhance Software Tools for Open Science

• NOT-OD-23-098: Notice of Special Interest: Administrative Supplements to NIH-funded T32 and TL1 Training Grants to Better Integrate Behavioral and Social Sciences (BSS) with other Health-Related Sciences

• PAR-23-120: Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)
  Application Due Date(s): May 15, 2023, May 15, 2024, May 15, 2025
  Expiration Date: May 16, 2025

• PAR-23-122: NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional)
  Application Due Date(s): September 8, 2023
  Expiration Date: September 9, 2023

• NOT-OD-23-082: Notice of Special Interest (NOSI): Administrative Supplements to Support Collaborations to Improve the AI/ML-Readiness of NIH-Supported Data

• NOT-OD-23-070: Notice of Special Interest (NOSI): Administrative Supplements to Support the Exploration of Cloud in NIH-supported Research
• The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)
  RFA-OD-22-028
  Application Due Date(s): December 19, 2022, November 22, 2023; November 22, 2024
  Expiration Date: November 23, 2024
   
• Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations
  NOT-MD-22-012
• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
  PAR-22-105
  Application Due Date(s): June 15, 2022, October 05, 2022, February 05, 2023, June 05, 2023, June 05, 2023, February 05, 2024, June 05, 2024, October 05, 2024, February 05, 2025
  Expiration Date: May 8, 2025
• Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
  PAR-22-106
  Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, February 16, 2025, June 16, 2025
  Expiration Date: September 8, 2025
• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
  PAR-22-109
  Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, October 16, 2024
  Expiration Date: February 16, 2025
• International Bioethics Research Training Program (D43 Clinical Trial Optional)
  PAR-22-116
  Application Receipt Date(s): June 6, 2024
  Expiration Date: June 7, 2024
   
• International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)
  PAR-22-118
  Application Receipt Date(s): June 6, 2024
  Expiration Date: June 7, 2024

• Notice of Intent to Publish a Funding Opportunity Announcement for a Data Management and Coordinating Center for Diagnostic Centers of Excellence (U2C Clinical Trial Not Allowed)
  NOT-NS-22-071

• Notice of Special Interest (NOSI): Administrative Supplements to Support Enhancement of Software Tools for Open Science
  NOT-OD-22-068

• Notice of Special Interest (NOSI): Administrative Supplements to Support Collaborations to Improve the AI/ML-Readiness of NIH-Supported Data
  NOT-OD-22-067

• Notice of Special Interest (NOSI): Support for existing data repositories to align with FAIR and TRUST principles and evaluate usage, utility, and impact
  NOT-OD-22-069

• Notice of Special Interest (NOSI): Administrative Supplements for Advancing the Ethical Development and Use of AI/ML in Biomedical and Behavioral Sciences
  NOT-OD-22-065

• Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed)
  NOT-HL-23-001

• Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional)
  NOT-OD-22-026

• Administrative Supplements to Promote Diversity in Research and Development  Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)
  PA-21-345
  Application Due Dates: Rolling
  Expiration Date: September 10, 2024

• Emerging Global Leader Award (K43 Independent Clinical Trial Required)
  PAR-21-251
  Application Due Dates: November 3, 2021, November 3, 2022, and November 3, 2023
  Expiration Date: December 12, 2023

• Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)
  PAR-21-252
  Application Due Dates: November 3, 2021, November 3, 2022, and November 3, 2023
  Expiration Date: December 12, 2023

• Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications
  NOT-EB-20-017

• Notice of Special Interest (NOSI): Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health
  NOT-EB-21-001
   
• Notice of Intent to Publish a Funding Opportunity Announcement for Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)
  NOT-MD-21-016

• Notice Announcing the National Human Genome Research Institutes Expectation for Sharing Quality Metadata and Phenotypic Data
  NOT-HG-21-022

• Notice of NIH Participation in Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science
  NOT-OD-21-011

• Notice of Special Interest (NOSI): Administrative Supplements to Support Enhancement of Software Tools for Open Science
  NOT-OD-20-073

• NIH Highlights Support for Data Science Research through the Academic Research Enhancement Award (AREA) Program
  NOT-GM-19-021 
   
• Notice of Special Interest in Research on the Health of Sexual and Gender Minority (SGM) Populations
  NOT-MD-19-001 
   
• National Science Foundation - National Institutes of Health NSF-NIH Interagency Initiative: Smart and Connected Health
  NOT-OD-18-149 
   
• National Science Foundation - National Institutes of Health NSF-NIH Interagency Initiative: Smart and Connected Health 
  NOT-OD-18-149 
   
• Announcing the High-Priority, Short-Term Project Award (R56) 
  • Notice of NHGRI's Participation in NOT-OD-04-047 "High Priority, Short-Term Project Award (R56)" 
    NOT-HG-17-004 [grants.nih.gov]