Research Funding Opportunities

To apprise the community of research areas that support that mission, NHGRI periodically publishes funding opportunities in the NIH Guide for Grants and Contracts. For your convenience, we have also listed the funding opportunities related to NHGRI on this webpage. NHGRI welcomes innovative investigator-initiated applications and encourages investigators with novel ideas to discuss potential applications with program staff during the concept development stage of the application. If you are considering applying for a Program Announcement with special review (PAR), a Request for Applications (RFA), or an application that exceeds $500K in direct cost in any one year, we encourage you to review the Guidance to Potential Applicants for NHGRI Support.

For how NHGRI will treat new and non-competing applications, see the NHGRI Funding Policy.

• Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed): PAR-25-228
  Application Due Dates: New: February 5, June 5 – 2025, 2026, 2027
  Renewal/Resubmission/Revision: March 5, July 5 – 2025, 2026, 2027
  Expiration date: September 8, 2027
  
  
• Investigator Initiated Innovation in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed): PAR-25-229
  Application Due Dates: New: February 16, June 16 – 2025, 2026, 2027
  Renewal/Resubmission/Revision: March 16, July 16 – 2025, 2026, 2027
  Expiration date: September 8, 2027
   
• Notice of Special Interest (NOSI): Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS): NOT-HG-24-040
   
• Notice of Special Interest (NOSI): Small Business Solutions to Enable Regional Genomic Medicine eConsult Services: NOT-HG-24-041
   
• Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application: NOT-HG-24-036
    
• Ethical, Legal, and Social Implications (ELSI) Congress (U13, Clinical Trials Not Allowed)
  RFA-HG-24-028
  Application Due Date(s): November, 19, 2024
  Expiration Date: November 20, 2024
   
• Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1), Clinical Trial Optional
  RFA-HG-24-026
  Application Due Date(s): November 15, 2024, August 1, 2025, July 31, 2026
  Expiration Date: August 3, 2026 
   
  • Notice of Pre-Application Webinar for Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1, Clinical Trial Optional): NOT-HG-24-038
     
• Advancing Genomic Medicine Research (R21 Clinical Trial Optional)
  RFA-HG-23-033
  Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025
  Expiration Date: February 12, 2025
   
• SBIR Solutions to Enable Population Genomic Screening (R43/R44 Clinical Trial Optional)
  PAR-24-263
  Application Due Date(s): December 2, 2024
  Expiration Date: December 3, 2024
   
• STTR Solutions to Enable Population Genomic Screening (R41/R42 Clinical Trial Optional)
  PAR-24-262
  Application Due Date(s): December 2, 2024
  Expiration Date: December 3, 2024
   
• Population Genomic Screening in Primary Care Sequencing Center (U01 - Clinical Trial Optional)
  RFA-HG-24-023
  Application Due Date(s): December 2, 2024
  Expiration Date: December 3, 2024
   
• Population Genomic Screening in Primary Care Cooperative Agreement (U01 - Clinical Trial Required)
  RFA-HG-24-021
  Application Due Date(s): December 2, 2024
  Expiration Date: December 3, 2024
   
• Population Genomic Screening in Primary Care Coordinating Center (U01 -Clinical Trials Optional)
  RFA-HG-24-022
  Application Due Date(s): December 2, 2024
  Expiration Date: December 3, 2024
   
• Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)
  PAR-23-301
  Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026
  Expiration Date: January 8, 2027
   
• Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)
  PAR-23-301
  Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026
  Expiration Date: January 8, 2027
   
• Investigator-Initiated Research in Genomics and Health Equity (R01 Clinical Trial Optional)
  RFA-HG-23-017
  Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal)
  Expiration Date: July 09, 2025
   
• Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional)
  RFA-HG-23-018
  Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal)
  Expiration Date: July 09, 2025
   
  • Notice of Extension of the First Receipt Date of RFA-HG-23-018: Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial (Clinical Trial Optional): NOT-HG-24-008
     
  • Notice of Pre-Application Webinar for the Investigator-Initiated Research in Genomics and Health Equity: RFA-HG-23-017 (R01 Clinical Trial Optional) and RFA-HG-23-018 (R21 Clinical Trial Optional): NOT-HG-23-049
     
  • Notice of Change to NHGRI-specific language in RFA-HG-23-018, Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional): NOT-HG-24-032
     
• Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
  PAR-23-184
  Application Due Dates: Applications are accepted by continuous receipt and are due by 5:00 PM local time of applicant organization. 
  Expiration Date: July 09, 2026
   
• Notice of Intent to Publish a Funding Opportunity Announcement for Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed): NOT-HG-23-028
   
• Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients’ Use of Genomic Information
  NOT-HG-22-011
   
• NHGRI’s Analysis, Visualization, and Informatics Lab-space (AnVIL) as an NIH-Designated Data Repository: NOT-HG-24-020

• Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required)
  PA-24-226
  Application Due Date(s): October 12, 2024, February 12, 2025, June 12, 2025, October 12, 2025, February 12, 2026, June 12, 2026, October 12, 2026, February 12, 2027, June 12, 2027
  Expiration Date: September 08, 2027
   
• Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)
  PA-24-225
  Application Due Date(s): October 12, 2024, February 12, 2025, June 12, 2025, October 12, 2025, February 12, 2026, June 12, 2026, October 12, 2026, February 12, 2027, June 12, 2027
  Expiration Date: September 08, 2027
   
• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
  PA-24-254
  Application Due Date: A change of recipient organization request must be made before the anticipated start date at the new organization and preferably several months in advance.
  Expiration Date: July 13, 2027
   
• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
  PA-24-253
  Application Due Date: A successor-in-interest request must be made before the anticipated start date at the new organization and preferably several months in advance.
  Expiration Date: July 18, 2027
   
• Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity)
  PA-23-217
  Application Due Date(s): December 08, 2023, April 08, 2024, August 08, 2024​​​​​​, December 08, 2024, April 08, 2025​​​​​​​, August 08, 2025
  Expiration Date: September 08, 2025​​​​​​​
   
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)
  PAR-21-357
  Expiration Date: January 8, 2025
   
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
  PAR-22-060
  Expiration Date: January 8, 2025
   
• Plans to Promote Safe Environments at Conferences Supported by NIH Grants and Cooperative Agreements
  NOT-OD-22-074

• NOT-OD-24-175: Reporting Data Management and Sharing (DMS) Plan Activities in Research Performance Progress Reports (RPPRs) Submitted on or After October 1, 2024
   
• NOT-OD-24-176: Updated Processes for Requesting Revisions to an Approved Data Management and Sharing (DMS) Plan
   
• NOT-OD-25-003: Reminder: Annual Reports to the Office of Laboratory Animal Welfare due December 1, 2024 
   
• NOT-OD-24-150: Request for Information (RFI) on Recommendations on Re-envisioning U.S. Postdoctoral Research Training and Career Progression within the Biomedical Research Enterprise
   
•  NOT-OD-24-084: Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025
   
•  NOT-OD-24-163: NIH’s Adoption of Common Forms for Biographical Sketch and Current and Pending (Other) Support by May 25, 2025
   
• Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed)
  RFA-OD-24-010
  Application Due Date(s): December 04,2024, June 04, 2025, December 04, 2025, June 04, 2026, December 04, 2026
  Expiration Date: December 05, 2026
   
• NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)
  RFA-OD-24-011
  Application Due Date(s): December 04,2024, June 04, 2025, December 04, 2025, June 04, 2026, December 04, 2026
  Expiration Date: December 05, 2026
   
• NOT-TR-23-026: Notice of Special Interest (NOSI): Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3) (Clinical Trial Optional) for Advancing Recruitment through Trial Innovation Network (AR-TIN)
   
• PAR-23-124: Genomic Community Resources (U24 Clinical Trial Not Allowed)
  Application Due Date(s): May 25, 2023, September 25, 2023, January 25, 2024, September 25, 2024, January 25, 2025, September 25, 2025, January 25, 2026
  Expiration Date: January 26, 2026
   
• PAR-23-166: Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
  Application Due Date(s): July 08, 2024, July 08, 2025, July 08, 2026
  Expiration Date: August 08, 2026
   
• NOT-OD-23-106: Revising the NIH/AHRQ/NIOSH Post-Submission Material Policy
   
• PAR-23-138: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
   
• PAR-23-171: Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)
  Application Due Date(s): May 15, 2023, May 15, 2024, May 15, 2025
  Expiration Date: May 16, 2025
   
• The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)
  RFA-OD-22-028
  Application Due Date(s): December 19, 2022, November 22, 2023; November 22, 2024
  Expiration Date: November 23, 2024
   
• Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations
  NOT-MD-22-012
   
• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
  PAR-22-105
  Application Due Date(s): June 15, 2022, October 05, 2022, February 05, 2023, June 05, 2023, June 05, 2023, February 05, 2024, June 05, 2024, October 05, 2024, February 05, 2025
  Expiration Date: May 8, 2025
   
• Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
  PAR-22-106
  Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, February 16, 2025, June 16, 2025
  Expiration Date: September 8, 2025
   
• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
  PAR-22-109
  Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, October 16, 2024
  Expiration Date: February 16, 2025
   
• Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed) NOT-HL-23-001
   
• Administrative Supplements to Promote Diversity in Research and Development Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 Application Due Dates: Rolling
  Expiration Date: September 10, 2024
   
• Announcing the High-Priority, Short-Term Project Award (R56) 
  • Notice of NHGRI's Participation in NOT-OD-04-047 "High Priority, Short-Term Project Award (R56)" 
    NOT-HG-17-004 [grants.nih.gov]