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The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… Genome Project (HGP) officially launched. I was there on the starting line, then a postdoctoral research fellow in the laboratory of genomics pioneer Maynard Olson at Washington University School of Medicine. The university was fortunate to have been … and accomplishments from the institute and the field of genomics. …
Research Funding
The Genomic Variation Program supports large-scale studies of human genetic variation.
… About 99.5 percent of a person's DNA is the same as any unrelated person's DNA. … the sequence of DNA among individuals are called genetic variation. Genomic variation explains some of the differences among … nucleotide polymorphisms (SNPs), indels, and other forms of genetic variation on a large scale across the genome. …
Event
NHGRI workshop seeking scientific perspectives for relating genomic variation to human phenotype.
… and Introduction Eric Green 8:40 - 9:00 a.m. Statement of Meeting Goals Elise Feingold Adam Felsenfeld Part I: … 2 ( Madison Room ) How and why to approach structural variation and other "hard to measure" variation? Co-Chairs : … Ecker Sharon Plon Katherine Pollard Moderated discussion on future NHGRI priorities for specific initiatives, data …
Staff
Dr. Stephanie Morris is a program director in NHGRI's Division of Genome Sciences.
… as a program director in 2019. She manages a portfolio of grants focused on high-throughput genomic technology development and functional genomics. She … of Excellence in Genomic Science (CEGS) program, and the Impact of Genomic Variation on Function (IGVF) program. IGVF, …
Fact Sheet
Genomic variation accounts for some of the differences among people, including important aspects of their health and susceptibility to diseases.
… The Big Picture  Genomic variation reflects the differences in a person’s DNA compared to other peoples’ DNA.  There are multiple types of variants in human genomes, ranging from small differences … evolving and advancing, including the regular development of new experimental technologies and data-analysis methods. …
Research at NHGRI
The Translational and Functional Genomics Branch explores the genetic, epigenetic and metagenomic basis of human disorders.
… Genomics Branch (TFGB) studies how genome structure and function contribute to health by exploring the genetic, epigenetic and metagenomic basis of human disorders. … TFGB researchers have developed a wide range of experimental and computational techniques to study all …
Educational Resources
A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next.
… Copy Number Variation (CNV) … A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next. … Chromosomes, Disease, DNA, Gene Variation … CNV) refers to a circumstance in which the number of copies of a specific segment of DNA varies among different …
Jobs at NHGRI
Funded postdoctoral positions are available in the laboratory of Dr. Shawn Burgess, within NHGRI's Translational and Functional Genomics Branch.
… postdoctoral positions are available in the laboratory of Shawn Burgess, Ph.D., within the Translational and Functional Genomics Branch of the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH). … The focus of the Burgess lab is on the genetics and functional genomics …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… A relatively new method of targeting specific DNA sequences in zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in humans, … June 5, 2015, and to be published in the July 2015 issue of Genome Research , the researchers reported that the …
News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
… In the first study of its kind, an international team of genomics researchers … of the human genome that are associated with skin color variation in some African populations, opening new avenues for research on skin diseases and cancer in all populations. … to cellular stress differently. National Institutes of Health researchers contributed to this effort, led by …