Search Results
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… DNA Sequencing … DNA sequencing is a laboratory technique used to determine the … Adenine, Cytosine, Guanine, Thymine, ACGT, DNA, DNA Sequencing … DNA sequencing refers to the general laboratory technique for … There are now several different methods available for DNA sequencing, each with its own characteristics, and the …
Organizational Structure
NHGRI’s Office of Genomic Data Science (OGDS) provides leadership, strategic guidance and coordination for NHGRI activities, programs and policies in genomic data science.
… backgrounds to help implement computational genomics and data science materials at their schools! October 2023 … The Office of Genomic Data Science (OGDS) was established in 2021 to: Develop, promote, support and coordinate genomic data science activities  across all parts of NHGRI. Serve as …
News Release
Researchers and clinicians are sequencing human genomes faster than ever, so considering the societal implications of genomic data is even crucial.
… we started generating massive amounts of human genomic data, there'd be lots of societal factors to consider. Now, researchers and clinicians are sequencing human genomes faster than ever, so considering the societal implications of genomic data and what we can learn from it is even more crucial. On …
Research Funding
​CSER is rapidly advancing the knowledge necessary to develop best practices for implementating genomic sequence data into clinical care. ​
… Reports of genomic sequencing being applied to the medical care of individual … but much more needs to be done before the use of sequence data becomes routine. Evidence regarding the most promising … most likely to be usefully addressed by a genomic sequencing approach still accumulating. Incorporation of …
Research at NHGRI
NHGRI researchers develop freely available software and analysis tools to help researchers around the world analyze and explore their genomic data.
… around the world analyze and explore their genomic data. These tools are free and openly accessible to anyone. … amplicons. bam2mpg A Bayesian genotype caller for NextGen sequencing data. BuddySuite A collection of four independent, yet … Data Tools and Resources …
Policies and Guidance
A webpage with information and associated FAQs that describe various expectations for data sharing that are specific to NHGRI-supported studies.
… human genomic studies, including those submitting data to AnVIL and studies with an Alternative Data Sharing Plan.  Follow the standard process outlined in … Submission Guide for instructions on submitting the data (Step 7).  For Step 2: Please complete the relevant …
Policies and Guidance
Frequently Asked Questions regarding the NHGRI's Metadata and Phenotypic Data Sharing Expectations.
… Data sharing is an important aspect of the research endeavor that ensures maximal use of participants’ data for scientific discovery, rigor and reproducibility, and more. NHGRI-funded researchers subject to NIH’s data sharing policies are expected to share comprehensive …
Event
The Encyclopedia of DNA Elements (ENCODE) Consortium presented a half-day workshop on the accessibility & utilization of ENCODE data.
… workshop on the accessibility & utilization of ENCODE data. The workshop included an introduction to the ENCODE project and resources available to access ENCODE data, as well as specific research applications using ENCODE data. Additionally, there was designated time for attendees …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… Landscape Originally published: January 13, 2022  Data sharing is central to the field of genomics. Both human and non-human genomic data have been widely shared through public data resources, such as the database of Genotypes and … genomic variation and gene expression. Because GTEx data can be shared for general research use, they are being …
News Release
The Clinical Sequencing Exploratory Research Consortium has offered an ethical framework to guide pediatricians in pursuing clinical sequencing studies.
… More than many other diagnostic technologies, genome sequencing carries the possibility of incidental or … information they should disclose, and to whom, when genome sequencing uncovers signs of possible genetic risk for … In a new analysis, a working group of the Clinical Sequencing Exploratory Research (CSER) Consortium has offered …