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About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… In 2003, an accurate and complete human genome sequence was finished and made available to scientists and researchers two years ahead of the original Human Genome Project schedule and at a cost less than the original … effort to sequence the 3 billion DNA letters in the human genome is considered by many to be one of the most ambitious …
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule. … the general laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. The … understanding the function of genes and other parts of the genome. There are now several different methods available for …
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
…  In 2003, the Human Genome Project ended with the generation of an essentially complete sequence of the human genome. The project took the practical approach of using the … 25 each year to commemorate the completion of the Human Genome Project in 2003 and the discovery of DNA's …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… researchers use a variety of tools to compare the complete genome sequences of different species. By carefully comparing … of years - is an important step toward understanding the genome itself. It pinpoints genes that are essential to life … protein is produced by any given gene is determined by the sequence in which four building blocks - adenine (A), thymine …
NEWS RELEASE
Cristina Kapustij, M.S., was named chief of the NHGRI's Policy and Program Analysis Branch.
… M.S., has been named chief of the Policy and Program Analysis Branch (PPAB) at the National Human Genome Research Institute (NHGRI). In her new role, she will … and Medicine; a policy analyst at the Institute for Genome Sciences and Policy at Duke University; and the …
Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… - called "bases" - that make up the DNA molecule. The sequence tells scientists the kind of genetic information … a particular DNA segment. For example, scientists can use sequence information to determine which stretches of DNA … which most DNA sequencing experiments are done. The human genome contains about 3 billion base pairs that spell out the …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… Vision — Generating and analyzing a complete human genome sequence will be routine for any research laboratory, … 92nd meeting of the National Advisory Council for Human Genome Research  will take place on February 22-23. As usual, … gene will be known; for non-coding elements in the human genome, such knowledge will be the rule rather than the …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… essentially unchanged in >20 years: provide contemporary genome-sequencing capabilities for intramural researchers at … that mission, regularly generating large amounts of genome-sequence data and analyses for numerous NHGRI and NIH … part of a group that was awarded a AAAS Prize for the analysis  of the Neanderthal genome. In 2012, NISC's …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… Why was it so difficult to fully complete the human genome sequence? The Human Genome Project ended in 2003, but genomic researchers had not … The human genome contains a massive amount of DNA. The human genome … can be represented by a letter (G, A, T or C). A genome's sequence cannot be read out end-to-end. Rather, researchers …
Event
Pre-application webinar on for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) data analysis validation centers funding opportunity announcement (FOA) on September 7, 2022.
… of Null Alleles in Cells (MorPhiC) Phase I: Data Analysis and Validation Centers (U01 Clinical trials not … The National Human Genome Research Institute (NHGRI) will host a pre-application webinar for the MorPhiC Data Analysis Validation Centers funding opportunity announcement …