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Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule. … the general laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. The … understanding the function of genes and other parts of the genome. There are now several different methods available for …
Organizational Structure
NHGRI’s Office of Genomic Data Science (OGDS) provides leadership, strategic guidance and coordination for NHGRI activities, programs and policies in genomic data science.
… backgrounds to help implement computational genomics and data science materials at their schools! October 2023 … The Office of Genomic Data Science (OGDS) was established in 2021 to: Develop, promote, support and coordinate genomic data science activities  across all parts of NHGRI. Serve as …
News Release
Researchers and clinicians are sequencing human genomes faster than ever, so considering the societal implications of genomic data is even crucial.
… Implications (ELSI) Research Program at the National Human Genome Research Institute, launched in 1990 with the … we started generating massive amounts of human genomic data, there'd be lots of societal factors to consider. Now, … cure auto-immune diseases or permanently change your DNA sequence. From NIH-NHGRI Thanks for the question! This is …
Research Funding
​CSER is rapidly advancing the knowledge necessary to develop best practices for implementating genomic sequence data into clinical care. ​
… frequent, but much more needs to be done before the use of sequence data becomes routine. Evidence regarding the most promising … and analyze evidence regarding the clinical utility of genome sequencing; 2) research the critical interactions … and Women's Hospital Robert C. Green Integration of Whole Genome Sequencing into Clinical Medicine Primary care …
Research at NHGRI
NHGRI researchers develop freely available software and analysis tools to help researchers around the world analyze and explore their genomic data.
… Researchers at the National Human Genome Research Institute have developed a number of software … around the world analyze and explore their genomic data. These tools are free and openly accessible to anyone. … Complementary Pairs Stability Selection for Genome-Wide Association Studies (ComPaSS-GWAS) An ad-hoc …
Policies and Guidance
A webpage with information and associated FAQs that describe various expectations for data sharing that are specific to NHGRI-supported studies.
… human genomic studies, including those submitting data to AnVIL and studies with an Alternative Data Sharing Plan.  Follow the standard process outlined in … Submission Guide for instructions on submitting the data (Step 7).  For Step 2: Please complete the relevant …
Policies and Guidance
Frequently Asked Questions regarding the NHGRI's Metadata and Phenotypic Data Sharing Expectations.
… Data sharing is an important aspect of the research endeavor that ensures maximal use of participants’ data for scientific discovery, rigor and reproducibility, and more. NHGRI-funded researchers subject to NIH’s data sharing policies are expected to share comprehensive …
Event
The Encyclopedia of DNA Elements (ENCODE) Consortium presented a half-day workshop on the accessibility & utilization of ENCODE data.
… workshop on the accessibility & utilization of ENCODE data. The workshop included an introduction to the ENCODE project and resources available to access ENCODE data, as well as specific research applications using ENCODE data. Additionally, there was designated time for attendees …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… Landscape Originally published: January 13, 2022  Data sharing is central to the field of genomics. Both human and non-human genomic data have been widely shared through public data resources, … Phenotypes (dbGaP), model organism databases (e.g., Mouse Genome Informatics and Xenbase ), and cloud repositories …
News Release
The Clinical Sequencing Exploratory Research Consortium has offered an ethical framework to guide pediatricians in pursuing clinical sequencing studies.
… More than many other diagnostic technologies, genome sequencing carries the possibility of incidental or … what information they should disclose, and to whom, when genome sequencing uncovers signs of possible genetic risk for … into clinical medicine, is funded by the National Human Genome Research Institute (NHGRI) and the National Cancer …