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Educational Resources
An oncogene is a mutated gene that contributes to the development of a cancer.
… is a mutated gene that contributes to the development of a cancer. … Carcinogen, Mutagen, Cancer, Cell, Mutation, Tumor Suppressor Gene … oncogene is a mutated gene that has the potential to cause cancer. Before an oncogene becomes mutated, it is called a … and it plays a role in regulating normal cell division. Cancer can arise when a proto-oncogene is mutated, changing …
News Release
NHGRI researchers find that specific abnormal chromosomal patterns in prenatal blood tests warrant whole-body MRI cancer screening.
… patterns in prenatal blood tests warrant whole-body MRI cancer screening. … — the presence of cancerous cells. “When she said cancer, I was in complete denial,” said Erica. “I was in the … pregnant person. In rare cases, the pregnant person has cancer. When a person has cancer, the tumor grows and sheds …
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
… found to be associated with inherited forms of breast cancer. … Breast Cancer, Prostate Cancer, Genetic Mutation, Genes, DNA Repair, Family Health … found to be associated with inherited forms of breast cancer and ovarian cancer. People with mutations in either BRCA1 or BRCA2 have a …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) … how the body signals the lack of oxygen in melanoma skin cancer, National Institutes of Health (NIH) researchers … acts as a sensor for oxygen and nutrients in many types of cancer. They discovered 40 new genes that are either turned …
Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… analyze and interpret DNA sequence information from cancer patients. They have developed an algorithm that sorts … to their clinical and biological relevance to a patient's cancer. … Human Genome Research Institute (NHGRI), and the National Cancer Institute, both part of the National Institutes of …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted … an association between AAV and the occurrence of liver cancer. The present research addresses this problem in gene … documented a 50-70 percent higher occurrence of liver cancer in AAV-treated mice compared with a 10 percent liver …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number of new … about the biology and development of a rare form of kidney cancer. … of the 66 ChRCC tumors studied, a high number for a rare cancer. The study revealed increased numbers of mitochondria …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… genomic research for NHGRI investigators. As head of the Cancer Genomics Unit, his research efforts led to the … The Cancer Genomics Unit (CGU) focuses on adopting genomic … in search of the gene responsible for early onset breast cancer ( BRCA1 ), CGU developed resources and aided in the …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… is a leader in the application of genome science to cancer research. His recent studies investigate the genetic … Asian Hepatocellular Carcinoma and Cholangiocarcinoma . Cancer Cell , 32(1):57-70.e3. 2017. Killian JK, Dorssers LC, … osteosarcoma profiling, melanoma profiling, breast cancer profiling, technology development …
Educational Resources
Pharmacogenomics is a branch of pharmacology concerned with using DNA and amino acid sequence data to inform drug development and testing.
… with using DNA and amino acid sequence data to inform drug development and testing. … with using DNA and amino acid sequence data to inform drug development and testing. …