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Educational Resources
A candidate gene is a gene whose chromosomal location is associated with a particular disease or other phenotype.
… to a gene that is believed to be related to a particular trait, such as a disease or a physical attribute. Because of … function, the gene is suspected to play a role in that trait, thus making it a candidate for additional study. …
Educational Resources
Mendelian inheritance refers to certain patterns of how traits are passed from parents to offspring.
Educational Resources
Autosomal dominance is a pattern of inheritance characteristic of some genetic diseases.
… Trait, Inherit, Genetic Diseases, Chromosomes, Mutation, …
Talking Glossary
Eugenics is a discredited belief that selective breeding for certain inherited human traits can improve the “fitness” of future generations. For eugenicists, “fitness” corresponded to a narrow view of humanity and society that developed directly from the ideologies and practices of scientific racism, colonialism, ableism and imperialism.
Educational Resources
Gene regulation is the process of turning genes on and off.
… Gene Expression, Genes, DNA, Transcription Factors …
Educational Resources
Chromatin is a substance within a chromosome consisting of DNA and protein.
… Chromosome, Histones, Gene Expression, DNA …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… Biochemistry, Gene Expression, Metabolism, Medication …
Staff
Vence Bonham is the acting deputy director for NHGRI and an associate investigator in NHGRI's Social and Behavioral Research Branch.
… methods and data types including qualitative interviews, quantitative survey methods, and biological data including … these findings. The Bonham group also studies sickle cell trait and sickle cell disease, a condition that affects … GJ, Brody LC. Screening student athletes for sickle cell trait--a social and clinical experiment. N Engl J Med , …
Educational Resources
A histone is a protein that provides structural support to a chromosome.
… Histones, DNA, Chromatin, Double Helix, Gene Expression … shape. Histones also play a role in the regulation of gene expression. …
Educational Resources
The Y chromosome is one of the two sex chromosomes that are involved in sex determination.
… X Chromosome, Y Chromosome, Phenotype, Fragile X Syndrome, Trait …