Search Results
News Release
NHGRI researchers have produced the first end-to-end DNA sequence of a human chromosome. The results show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers to produce a complete sequence of the human genome.
… of Health (NIH), have produced the first end-to-end DNA sequence of a human chromosome. The results, published … produced. However, there are hundreds of gaps or missing DNA sequences that are unknown. These gaps most often contain … incredibly long, consisting of about 6 billion bases, DNA sequencing machines cannot read all the bases at once. …
News Release
Ten investigators will receive exome sequencing data as part of their clinical research projects at the NIH Clinical Center.
… Ten intramural investigators will receive exome sequencing data as part of their clinical research projects … NIH Clinical Center. Using CCGO funds, the NIH Intramural Sequencing Center will sequence the exomes of 1,000 NIH … that codes for proteins, the most likely place to find DNA differences that could cause or contribute to disease. …
News Release
On April 25, National DNA Day, the National Institutes of Health (NIH) will welcome a new statue, “The Ladder,” celebrating DNA and children.
… On April 25, National DNA Day, the National Institutes of Health (NIH) will welcome a new statue, “The Ladder,” celebrating DNA and children. National DNA Day is a unique day when students, teachers and the … New DNA statue to be unveiled at NIH on National DNA Day …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
… Techniques to modify DNA in the genome have existed for several decades, but the … of genome editing in humans, the main application of this technology has been in basic research. Editing the genomes of … information between two similar (homologous) strands of DNA. 1 Scientists began developing this technique in the …
News Release
NIH lost a key member of its broader genomics team when Robert Blakesley, Ph.D., director of the NISC sequencing group at NIH, retired on Dec. 31, 2015.
… collect biological samples, purify and sequence the DNA and analyze the resulting data. The National Institutes … 31 retirement of Robert Blakesley, Ph.D., director of the sequencing group at the NIH Intramural Sequencing Center (NISC) in Rockville, Maryland. …
Educational Resources
Ancestry-informative markers are sets of polymorphisms for a DNA sequence found in different frequencies between populations from different geographical regions.
… markers are sets of polymorphisms for a DNA sequence found in different frequencies between … Ancestry, Genome, Family Health History, Genotype, DNA Sequence … markers are sets of polymorphisms for a particular DNA sequence that appear in substantially different …
Events
The National Human Genome Research Institute (NHGRI) hosted the Advanced Genomic Technology Development Meeting at Northeastern University in Boston, Massachusetts, on May 29 - 31, 2019.
… Research Institute (NHGRI) hosted the Advanced Genomic Technology Development Meeting at Northeastern University in … of genomic technologies including those for nucleic acid sequencing. The meeting brought together NHGRI Genomic … who had insights that would help to achieve the goal of sequencing human genomes at high quality for much less than …
News Release
Researchers, clinicians, and computational biologists meet to consider future opportunities for NHGRI's Genome Sequencing Program.
… Human Genome Research Institute's (NHGRI) flagship Genome Sequencing Program (GSP) at a July 28 - 29 meeting in … The workshop, "Future Opportunities for Genome Sequencing and Beyond: A Planning Workshop for the National … computational tools for genome analysis, ranging from DNA sequence processing to variant prediction and annotation. …
Genomics Teaching Tool
An activity that demonstrates how DNA can be isolated from a strawberry using common household items.
… plants, animals and bacteria. Deoxyribonucleic acid , or DNA, is the molecule that controls everything that happens in the cell. DNA contains instructions that direct the activities of cells … body. With only a few household items, you can extract DNA from strawberries just about anywhere! Extracting DNA …
Research Funding
The Genome Sequencing Program uses genome sequencing to identify genes and genomic variants underlying human inherited disease.
… The Genome Sequencing Program is consists of the following centers … The NHGRI Genome Sequencing Program (GSP) has evolved from NIH's participation … in the scientific questions that could be addressed as the technology (cost, quality) changed over time. The GSP aims to …