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Fact Sheet
Pharmacogenomics is a growing area of genomic medicine that uses a patient's genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.
… More than 6% of hospital admissions are due to adverse drug reactions, and avoiding such adverse reactions using … alters the protein and slows this transport, causing the drug to build up in the blood and leading to pain and muscle … the HER2 receptor can also be a target for treatment. The drug trastuzumab (one common brand name of which is …
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… Adeoye AM. Genetics of hypertension treatment response in drug naïve newly diagnosed hyperte nsives. 3. Ahmed DF . …
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.
News Release
Researchers identified 13 gene regions that influence cholesterol levels, some of which affected people differently if they are smokers or former smokers.
Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
Talking Glossary
GMO (short for “genetically modified organism”) is a plant, animal or microbe in which one or more changes have been made to the genome, typically using high-tech genetic engineering, in an attempt to alter the characteristics of an organism.
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
For Patients and Families
Clinical research is research conducted with human subjects, or material of human origin, in which the researcher directly interacts with human subjects.
… phases: In Phase I clinical trials, researchers test a new drug or treatment for the first time in a small group of … side effects. In Phase II clinical trials, the study drug or treatment is given to a larger group of people (about … patients with the particular disease, to see if the drug or treatment is effective, and to further evaluate its …
News Release
Ten investigators will receive exome sequencing data as part of their clinical research projects at the NIH Clinical Center.