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News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… modifications of DNA, proteins that bind to DNA, and RNA (a sister molecule to DNA) interact to regulate genes. … types, such as long-range DNA interactions and protein-RNA interactions." As a new feature, ENCODE 3 researchers …
News Release
NIH researchers researchers and collaborators have gained some key insights into the biological inner-workings of regrowing a body, the evolution of aging and a unique method to dispose of aging cells, by studying the genomes of a hermit crab (Hydractinia symbiolongicarpus).
… new body from only its mouth. The researchers sequenced RNA from Hydractinia symbiolongicarpus , a small, tube-shaped … far from the its mouth. Credit: Darryl Leja, NHGRI.  When RNA sequencing pointed to senescence, the researchers scanned …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… of the ENCODE pilot project. Antibodies that recognize RNA polymerase II and TAFII250, a component of a general … that initiates the preinitiation complex assembly for RNA polymerase II, should be bound to the promoters of all genes actively transcribed by RNA polymerase II. The RNA polymerase II antibody is …
File
… Expression Analysis, Functional Enrichment, and Network Inference_042716.pdf …
Funding Opportunities
Funding Opportunities for Investigator-Initiated Research in Computational Genomics and Data Science
The Computational Genomics and Data Science Program Announcements (PARs) invite applications for investigator-initiated research efforts fostering innovation in computational genomics, data science, statistics, bioinformatics, and data visualization and exploration.
… ARIZONA Enabling comprehensive and user-friendly circular RNA analyses with circtools.cloud HG013124 PARK, PETER J … model and software implementation for analysis of nascent RNA sequencing data HG012944 GREENLEAF, WILLIAM JAMES … UNIVERSITY HEALTH SCIENCES Tensor Array Methods for RNA-Seq Analysis HG010731 GUSEV, ALEXANDER DANA-FARBER CANCER …
National Advisory Council for Human Genome Research
The Director's Report-Related Documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in February 2023.
… Awards 24 NASEM Study: Toward Sequencing and Mapping of RNA Modifications NASEM RNA Study Website NASEM RNA Workshop Recording 25 Global Alliance for Genomics and …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… (1) developing a protocol to isolate high quality DNA and RNA from a bank of stabilized tissue samples collected as …
Staff
Dr. Shurjo Sen is a program director in NHGRI's Division of Genome Sciences who manages a portfolio of grants focused upon genomic data sciences, and is particularly interested in transitioning genomics from a centralized data repository model to cloud-based collaborative science.
… R, Munson PJ, McVicar DW, Biesecker LG. Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery …
Staff
Dr. Laura Elnitski is a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
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… A central focus is the intersection of DNA methylation, RNA splicing, and chromatin architecture in shaping gene … research helped identify Suppression of Splicing (SOS), an RNA quality control mechanism that prevents premature stop … R. A novel role for nucleolin in splice site selection . RNA Biol . 2022;19(1):333-352. doi: …
Staff
Dr. Jean Gao is a Program Director in NHGRI's Office of Genomic Data Science.
… Mid-Career Advancement (MCA), the Dark Dimensions for the RNA Regulome (D2R2) Ideas Lab, and Pathways to Enable …