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News Release
NHGRI published its “Strategic vision for improving human health at The Forefront of Genomics” in the journal Nature. This vision describes the most compelling research priorities and opportunities in human genomics for the coming decade, signaling a new era in genomics for the Institute and the field.
… The first area represents a compilation of nine major principles and values that provide a guiding compass … community must improve in the coming decade. Some of the complex genomic issues discussed in the new vision relate to …
Educational Resources
A histone is a protein that provides structural support to a chromosome.
File
… genes of unknown function, 3 SNPs in HLA -A – class 1 MHC 71% prevalence in asymptomatics compared to 29 % in …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… affect how the body processes drugs, while others play a major role in how a fertilized egg develops into a baby. … will take years of research to identify and understand the complex connections among all the molecules in all biological … the prospect of fighting many enemies. Fortunately, this complex view can be simplified by looking at which biological …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… focuses on a spectrum of disorders from those that have a major public health impact to rare genetic conditions with … impacts the flow of information and support across complex social systems. Health disparities We conduct …
News Release
NHGRI researchers have generated the largest catalog of genetic variants associated with physical traits for domesticated dog breeds.
… breeds. The sheer number of dog breeds points toward the major role played by genetics in shaping such variation in …
The Genomics Landscape
In the January 2019 edition of The Genomics Landscape, NHGRI Director Dr. Eric Green honors NIAMS Director, Stephen Katz, M.D., Ph.D.
… and genomics. Later this month, NHGRI is hosting our first major strategic planning workshop, entitled "From Genome to … as NIAMS Director, Steve ably led the Institute and made major research contributions related to numerous important … is needed from both NIH and external sources; (2) one major challenge to genomic medicine implementation is the …
The Genomics Landscape
In the January 5, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how artificial intelligence and machine learning are becoming omnipresent throughout NHGRI and in genomics.
… scholarly perspectives about multiple issues related to complex areas of social and behavioral genomics. All the … setting the stage for widespread adoption of AI to tackle complex biomedical challenges beyond human intuition. The … and healthcare research. Bridge2AI includes projects with major genomics components. Ten years ago, it was hard to …
Fact Sheet
A fact sheet detailing how the project began and how it shaped the future of research and technology.
… required the work to be concentrated in a modest number of major centers to maximize economies of scale. Before the … was an instrumental planner, prominent leader, and major participant of the Human Genome Project. (NHGRI Photo … greatly advanced this basic method through a series of major technical innovations. Photo: Dr. Collins analyzing …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease.
… in finding genetic variations that contribute to common, complex diseases, such as asthma, cancer, diabetes, heart … 2006. The initial studies include bipolar disorder, major depression, kidney disease in type 1 diabetes, … National Institute of General Medical Sciences, also are major contributors to the PharmacoGenetics Research Network. …