Search Results
Research at NHGRI
CRGGH uses genomic tools to understand the pathobiology of metabolic disorders, including obesity, hypertension, diabetes, dyslipidemia, and kidney disease.
… dyslipidemia, and kidney diseases, in different human populations with particular attention to African Americans and Africans. Recent African origin populations, such as African Americans, provide unique … genetic and environmental levels in contemporary African populations, the CRGGH is developing biological and …
Research at NHGRI
CRGGH develops a comprehensive staff and training program that uses genomic approaches to study human health and to reduce/eliminate health disparities.
… given to the inclusion of scholars from underrepresented populations. … health importance. He believes that studying diverse human populations is critically important in the global effort to … variation and its link to disease risks in different populations. For example, how does human genetic variation …
News Release
Researchers recommend more rigorous clinical study of dietary management practices for patients with IEMs, which may result in reformulating some medical foods.
… serious and life-threatening complications. However, such special foods may cause harm in some patients when their use … patients received part or all of their nutrition from a special mix of natural protein and MMA medical foods … Strauss, M.D., and Holmes Morton, M.D., of the Clinic for Special Children in Strasburg, Pennsylvania, to help model …
News Release
NIH is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care for all individuals.
… individuals and groups, including diverse and underserved populations, and in healthcare settings that extend beyond … could potentially be put into practice. "Engaging patient populations that are traditionally underrepresented in … that covers geographical areas from the racially diverse populations in Houston, to the underrepresented minority …
For Patients and Families
The partnership engages communities on genomics, informs and shares perspectives, and impacts the focus of research.
… liaisons and health advocates representing diverse populations to engage communities on genomics, inform and … liaisons and health advocates representing diverse populations to engage communities around genomic science, to …
FAQ
On August 23, 2023, the National Human Genome Research Institute hosted a pre-application webinar for the Investigator-Initiated Research in Genomics and Health Equity RFAs: RFA-HG-23-017 and RFA-HG-23-018.
… Would genomics/multi-omics sample sizes of XXX in X populations be competitive? Would creating a minority cohort … that is relevant to advancing health equity in U.S. populations. Foreign components, as described in Section III. … focus on the application must be on health equity in U.S. populations. …
Research Funding
NHGRI solicits grant applications that relate to its scientific priorities and research interests
… review and award. NIH institutes and centers also publish special grant solicitations targeted toward specific research … submission, review and award. Program announcements with special receipt dates (PAR) provide their own submission …
Event
On November 16-17, 2023, the National Human Genome Institute will co-sponsor a workshop, Advances in the Genetic Architecture of Complex Human Traits, to take a historically grounded and forward-looking approach towards dissecting the genetic architecture of complex traits in humans.
… for example, more affected? Session 3 – Families, Populations, and Societies The resemblance among relatives … a.m. Session Three: Genetic Architecture – Families, Populations, and Societies Chair: Iain Mathieson, University … 9:55 a.m. An Epidemiological Lens on Precision in Study Populations and Questions for Genetic Research Gen Wojcik, …
Health
A polygenic risk score is one way by which people can learn what their risk of developing a disease is, based on the total number of genomics variants related to the disease.
… the role that genetics plays in diseases across different populations. A “ polygenic risk score ” is one way by which … may not be adequate data about genomic variants from other populations for calculating a polygenic risk score in those populations. This historic lack of diversity in genomic …
News Release
NIH is establishing the Multi-Omics for Health and Disease Consortium, with approximately $11 million awarded in the consortium’s first year of funding. The new consortium aims to advance the generation and analysis of “multi-omic” data for human health research.
… for clinical studies involving ancestrally diverse populations. …