Most grant applications submitted to the National Institutes of Health (NIH) for research or research training are investigator-initiated proposals. These proposals are considered unsolicited, and follow the NIH standard schedule for submission, review and award.
NIH institutes and centers also publish special grant solicitations targeted toward specific research interests and priorities. Program announcements (PA) describe new, continuing or expanded program areas, and follow the standard schedule for submission, review and award. Program announcements with special receipt dates (PAR) provide their own submission schedules. Requests for Applications (RFA) solicit proposals for more targeted research interests, and each specifies a single receipt date.
NIH encourages applicants to contact the specific institute or center (IC) from which they seek funding. If an applicant wishes to submit a proposal with a budget of $500,000 or more in direct costs for any one year, preliminary contact with the IC is required. Individual PAs and RFAs include contact information.
To contact the NHGRI Extramural Program:
Phone: (301) 496-7531
NIH forms and applications are available online. NIH encourages applicants to obtain applications and instructions via the Internet in order to stay informed of the latest updates and revisions to these documents.
Individual NRSA Fellowship Application Form PHS 416-1 is another commonly used form.
Note: NIH is converting from the PHS 398 to the SF424 form AND electronic submission through Grants.gov! To do business with the NIH in the future, grantees MUST register with both Grants.gov AND the NIH eRA Commons.
See detailed info at: NIH Announces Initial Plans to Transition to the SF424(R&R) Application and Electronic Submission through Grants.gov. For updates regarding the transition: Electronic Submission of Grant Applications.
To be considered for funding, applications must be sent or delivered by the established receipt dates to the NIH Center for Scientific Review (CSR). For those applications in response to a specific IC solicitation, the announcement may require that copies be sent to the IC as well.
For videos and resources for grant applicants, visit the CSR Applicant Resources. For answers to frequently asked questions about electronic submission of nih grants, compiled by OER, view the FAQ About Electronic Grant Submission.
Center for Scientific Review
National Institutes of Health
6701 Rockledge Drive, Room 1040, MSC 7710
Bethesda, MD 20892-7710
Bethesda, MD 20817 (for express/courier service)
Phone: (301) 435-0715
New Limits on Appendix Materials for All NIH/AHRQ/NIOSH Grant Applications Beginning with Receipt Dates On or After January 3, 2007.
- Center for Scientific Review (CSR) Applicant Resources
Videos and resources for grant applicants from the Center for Scientific Review.
- FAQ About Electronic Grant Submission
Offers answers to frequently asked questions about electronic submission of nih grants, compiled by OER.
- Grant Writing Tips Sheet
Guides and tip sheets from NIH institute websites.
- NIH Grants Policy Statement
Gives detailed information concerning all aspects of grants and awards processes at NIH.
- NIH Office of Extramural Research (OER)
The NIH grants HOME page, and the Center for Scientific Review [public.csr.nih.gov] offer detailed accounts of the grant application and review processes.
- Office for Human Research Protections (OHRP)
OHRP provides clarification and guidance to research institutions, develops educational programs and materials and promotes innovative approaches to enhancing human subject protections.
- New and Early Stage Investigator Policies
A website that articulates NIH's continuing commitment to new investigators. The website describes current policies, data related to the influx of new investigators, resources that new investigators can use to understand and work with the NIH, and helpful hints that might be useful in constructing a first application for NIH support.
Last updated: March 17, 2022