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The Genomics Landscape
In the November 2023 edition of The Genomics Landscape, NHGRI Director Eric Green, celebrates the 30th anniversary of the NHGRI Intramural Research Program as well as announces the launch of a new digital history archive.
… changes in cis and trans and the evolution of gene expression in humans and chimpanzees Barr et al. Genome Biol … researchers at the University of Chicago highlight tissue-specific regulation of genes that lead to differences … transcription factors — proteins that regulate the expression of genes — that function differently between the …
File
… Intramural Research Program Director’s Report Outline Genotype-Tissue Expression (GTEx) Document 39 Enrollment complete (965 …
Research Funding
A list of members who contribute to the goals of the IGVF Consortium by generating data and/or analyses, sharing data and/or analyses freely through the IGVF Data and Administrative Coordinating Center (DACC), and/or by contributing to cross- consortium integrative analyses.
… autoimmune diseases affect genome function and gene expression in human germinal centre B cells. They are … affect epigenetic regulatory networks and disrupt gene expression in complex diseases. Xuanyao Liu, University of … lab is to design interpretable AI methods for discovering genotype to phenotype mappings for clinical applications; …
File
… Slides_Epigenetic effects and gene expression.pptx …
News Release
In a new large-scale genetic analysis, National Institutes of Health (NIH) scientists have found set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type 2 diabetes.
… the largest sequenced-based analysis of microRNA expression in human pancreatic islets to date,” said Francis … the stage for understanding how microRNAs fine-tune gene expression in pancreatic islets and its implications for … the largest sequenced-based analysis of microRNA expression in human pancreatic islets to date. The results of …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… signs of damage. Their metabolism and pattern of gene expression were different from those of healthy cells, … The research team reported that the metabolism and gene expression of the crucial TFH cells are still "largely … transcription factor known as Blimp1. TCF1 turns off expression of Blimp1, just as Blimp1 turns off expression of …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in September 2019.
… Website International Mouse Phenotyping Consortium 29 Genotype-Tissue Expression Project (GTEx) GTEx Portal Database of Genotypes …
Staff
Binta Jalloh is a postdoctoral fellow at the Center for Research on Genomics and Global Health (CRGGH).
… Cancer Institute’s Laboratory of Receptor Biology and Gene Expression doing single molecule tracking to understand the … of transcription factors important for regulating gene expression in live budding yeast. Her primary role in the … under Dr. Quinn Vega studying signal transduction and gene expression using bacterial cells. Prior to coming to the USA, …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data.
… the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene … University of Massachusetts Medical School Rules Of Gene Expression Modeled On Human Dendritic Cell Response To …