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The Genomics Landscape
In the November 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the important genomics legacy of the Human Heredity and Health in Africa (H3Africa) program as it comes to an end.
… with the aim of developing a sustainable and collaborative African genomics research enterprise. With most of its … and the UK Wellcome Trust (in strong partnership with the African Society for Human Genetics ), H3Africa has fostered … from K. Sean Kimbro, Ph.D. , about health disparities and ancestry-driven drug discovery. This month will feature …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… Zhou J, McLeod H, Adeyemo A, Rotimi CN. Pharmacogenomics, ancestry and clinical decision making for global populations. … variants with ethnicity-specific effects in African Americans. PLoS Genet. 2014 Mar 6;10(3):e1004190. … new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun;45(6):690-6. doi: …
Event
On October 25-29, 2022, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.
… Traits Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Research Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Genetics and Genetic Epidemiology Developing an African American population-based transcriptome predicion …
Research at NHGRI
A list of publications led by or in collaboration with the Center for Research on Genomics and Global Health.
… polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. Cell Genom . … of community gatekeepers about genomic risk information in African cleft research. BMC Public Health . 24(1):507. 2024. … [ PubMed ]  Wonkam A, Adeyemo A . Leveraging our common African origins to understand human evolution and health. …
Profile
Dr. Hanchard talks about his journey into genetics research, his collaborations with international researchers, and the importance of determination in science.
… the genomics and environmental contributors of diseases in African populations. Diversifying genomics research is at the … Dr. Hanchard studies are more common in individuals of African ancestry. In fact, diversity is at the core of his research …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… and association with obesity in West Africans and African-Americans. Diabetes 59(6):1549–1554. PMCID: … 2010. Genome wide association of anthropometric traits in African and African derived populations. Hum. Mol. Genet. … association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet ., …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
…  … Polygenic scoring accuracy varies across the genetic ancestry continuum Ding et al. Nature . 2023 … that involve data generated from individuals of European ancestry, but such studies are limited in their applicability … training, and ethical guidelines to support sustainable African research. Dr. Troyer also co-managed the …
The Genomics Landscape
In the February 2, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the new NIH Data Management and Sharing (DMS) Policy and how it emphasizes the importance of good data management practices.
… 2022. PMC9793425  One method for studying the ancestry of a human population involves the use of DNA from … resources . …  The Smithsonian’s National Museum of African American History and Culture (NMAAHC) will host the … this program, panelists will explore the work of Black and African American millennial scientists conducting …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… architecture of complex traits among populations of African ancestry. Using her multidisciplinary background, she aims to …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… the collected data was mostly from people of European ancestry (due to limited availability of diverse datasets … polygenic risk scores were also applicable to people of African ancestry, which was confirmed through analyzing data from …