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Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… resource for defining the biological significance of ancestry-related genomic variation in African-Americans. … GENE-FORECAST® will test the working … between the distinct genomic variation characteristic of African-Americans (AA) and the exposome of social …
Educational Resources
Ancestry-informative markers are sets of polymorphisms for a DNA sequence found in different frequencies between populations from different geographical regions.
Ancestry-informative Markers … Ancestry-informative markers are sets of polymorphisms for a … between populations from different geographical regions. … Ancestry, Genome, Family Health History, Genotype, DNA …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… the risk of other diseases in Africans and people of African descent. Mutations in the gene APOL1 , for example, … to offer protection against the pathogen that causes African sleeping sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… underpinnings of obesity in continental Africans and African Americans. They discovered that approximately 1 percent of West Africans, African Americans and others of African ancestry carry a genomic variant that increases their risk of …
15 Ways Genomics Influences Our World
Genomics is illuminating human and family origins at a level not previously possible.
… way to decipher the various stories of human origins and ancestry. … Nearly 20 years ago, scientists developed … Carlos Bustamante's research groups  showed in 2010 , an African American individual in the United States has, on average, about 75-80 percent West African ancestry and about 20-25 percent European ancestry. …
News Release
More research must be done to understand the interactions of ancient genes with modern environments.
… the risk of other diseases in Africans and people of African descent. Mutations in the gene APOL1 , for example, … to offer protection against the pathogen that causes African sleeping sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of …
Talking Glossary
Understand the terms and concepts used in genetic research
… Genetic Ancestry … Genetic ancestry refers to information about the people that an … from, including their genetic relationships. … Genetic ancestry refers to information about the people that an …
News Release
An international team of researchers including NIH has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa.
… clues to medical conditions in people of sub-Saharan African ancestry, and indicates that the migration from Africa in the … data to explore the genomic-variation landscape of several African ethno-linguistic groups. A genotype is a subset of a …
News Release
The largest genomic study on type 2 diabetes in Africans to date has recently been published in Nature Communications and reports the most recent findings of the ongoing Africa America Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades.
… of the Genomics of Type 2 Diabetes in Africans Identifies African-specific Risk Locus … The largest genomic study on …
News Release
This publication and the release of the accompanying data address knowledge gaps across genomics and are certain to have a continuing impact in the field.
… in Nature addresses this lack with a study of 426 African individuals, representing 50 ethnolinguistic groups. … with WGS data from the 1000 Genomes Project and the African Genome Variation Project are included for comparison … (grey circles). 1000G, 1000 Genome Project; AGVP, African Genome Variation Project. Figure originally published …