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News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… Bruce Agnew … For many cancer patients and their doctors, the deadliest enemy is metastasis - the migration of cancer cells from the original tumor to other places in the body. In at least 90 percent of hard-tumor cancer …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Kyle Davis … Receiving a cancer diagnosis can feel like losing control of everything. In the wake of such a diagnosis, patients, family and friends … its natural defenses, which can then lead to diseases like cancer," said Laura Elnitski, Ph.D., a senior investigator in …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's lexicon begin with the letter "r": … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … confirmed that PTCs are driven primarily by mutations in one of two cancer-associated genes: BRAF (and a particular …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… NHGRI Communications and Public Liaison Branch … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to … aggressive cancers, including prostate, endometrial, bladder, lung, head and neck, and gastric cancers. They also … tumorigenesis. They search for causal sequence variants in DNA from inherited cells of at-risk individuals, in human …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation … will next begin screening blood samples from patients with bladder, breast, colon, pancreatic and prostate cancers to …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… Jeannine Mjoseth … How well cancer patients fare after chemotherapy can be affected by … Institutes of Health, and the University of Oxford in the United Kingdom. … Cancer patients were a little more likely to survive for five …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Steven Benowitz … Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… Jeannine Mjoseth … A repurposed cancer drug appears to reduce the severity of lesions and … disease. The drug, miransertib, was well tolerated, even in children, according to a National Institutes of Health … goal in using the drug was very different from its use in cancer therapy. In cancer, the objective is to eliminate all …