Search Results

1 - 10 of 35
Staff
Lisa Garrett is a staff scientist and director of the NHGRI Transgenic Mouse Core.
… includes maintaining an updated guide for protocols using crispr/cas9 and other gene-editing tools. this guide is provided on … more recently gene editing using site-specific nucleases (crispr/cas9). the core breeds, in-house, 90 percent of the …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… reported that the gene-editing technology known as crispr/cas9 is six times more effective than other techniques at … specific sequences. the study also demonstrated that the crispr/cas9 method can be used in a "multiplexed" fashion - …
News Release
Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from harmful DNA viruses, strengthening the plant's protections.
… scientists are using an exciting gene editing tool called crispr/cas9 to protect plants from harmful dna viruses. the crispr/cas9 system has previously been adapted for use in …
News Releases
Researchers explored patients', parents' and physicians' perspectives on the use of CRISPR-Cas9 gene-editing to reverse sickle cell disease.
… parents' and physicians' perspectives on the use of  crispr-cas 9 gene-editing to reverse sickle cell disease (scd).  … a first-of-its-kind study crispr-cas 9 is a gene editing technology that researchers … counsel from when deciding whether to participate in a crispr-based clinical trial. "researchers should forge …
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… editing, the scientific background of gene editing and crispr in particular, the clinical applications of gene … among the protocols was one that proposed the use of crispr to edit the t cells (a type of immune cell) of … create multiple, simultaneous gene knockouts using crispr/cas9 in zebrafish (varshney, et al., 2015). the lab has also …
News Release
NHGRI hosted a CRISPR "Ask Me Anything" with Jennifer Doudna, Ph.D., reaching 10.5 million people worldwide.
… national human genome research institute (nhgri) hosted a crispr "ask me anything" (ama) with jennifer doudna, ph.d., … the world and three billion monthly page views. … using crispr to treat diseases dr. doudna, along with program … for crispr clinical trials would include using cas9 proteins from different bacterial species, which humans …
News Release
In a study published in the journal Science, collaborators at NHGRI, the National University of Ireland, Galway, and the Whitney Laboratory for Marine Bioscience at the University of Florida, Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ cells in a cycle that can repeat endlessly.
… perpetual germ cell production. the researchers used the crispr-cas 9 gene-editing technique to remove tfap2 from … adult stem cells, whole-genome sequence data, crispr-cas 9, gene-editing … in a study published in the …
Policy Issues
Patients with genetic disorders and members of the public have diverse about germline genome editing.
… "compelling medical applications justifying the use of crispr/cas9 in embryos." 3 in july 2017, using non-federal funding, … huang and sun yat-sen of university in guangzhou used crispr on nonviable embryos from local fertility clinics in …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing ​
… of health (nih) are adopting newer techniques, such as crispr, to conduct their investigations. a robust … knowledge and ability to edit genomes for many years, but crispr technology has brought major improvements to the … recognize specific genome sequences and cut them via the cas9 protein, a protein that works with crispr and that has …
Policy Issues
Genome editing is currently being applied to research on cancer, mental health, rare diseases, and many other disease areas.
… gene therapy has grown tremendously since the discovery of crispr, the vast majority of work undertaken by scientists … effects are still unknown, even for a technology like crispr that is many times more precise than previous … editing, gene therapy, treating disease with gene editing, crispr-cas 9, crispr … genome editing is currently being …