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Event
NHGRI commemorates the life and legacy of genomics champion Representative Louise M. Slaughter (D-N.Y.), who passed away in March 2018, by naming an annual National DNA Day lecture at the National Institutes of Health (NIH) in her honor.
News Release
Scientists studying the genomes of nearly 5,000 people have pinpointed a genetic variant tied to an increased risk for stroke and cardiovascular disease.
… metabolic pathway that plays a major role in several common diseases. Together, their findings may provide new … treatment of stroke, cardiovascular disease and many other common diseases," said Stephen R. Williams, Ph.D., a … acid homocysteine are associated with an increased risk of common diseases such as stroke, cardiovascular disease and …
The Genomics Landscape
NHGRI medical genetics training programs provide an array of education opportunities
… elements in the human genome, such knowledge will be the rule rather than the exception. Lastly, on March 26, Pilar … elements in the human genome, such knowledge will be the rule rather than the exception. Speakers: Nancy Cox, Ph.D., … exposes its trainees to genetic conditions that range from common to ultra-rare, providing broad experiences in clinical …
Research at NHGRI
CRGGH uses genomic tools to understand the pathobiology of metabolic disorders, including obesity, hypertension, diabetes, dyslipidemia, and kidney disease.
… genes interact with "new" environments in the evolution of common complex traits. … View a list of publications led by … Briefly, it is implemented in four stages. First, all common variants in a pre-specified region (e.g., gene) are … inclusion and exclusion of that RV. Lastly, significant common and rare variants, along with covariates, are included …
Policy Issues
NHGRI has created the IDE Greenhouse as an educational resource to help increase understanding of the regulation in the genomics context.
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in … African-American background: Prostate cancer is more common in African American men, than in men of other racial …
News Release
NIH researchers have identified and tested a molecule that shows promise as a possible treatment for Gaucher disease and Parkinson's disease.
… treatment for the rare Gaucher disease and the more common Parkinson's disease. Ellen Sidransky, M.D., a senior … are at higher risk of developing Parkinson's disease, a common disorder characterized by tremors, muscular rigidity … disease can have direct relevance to the treatment of common disorders like Parkinson's disease ." Researchers will …
Policy Issues
In 2008, the Genetic Information Nondiscrimination Act was passed into law, prohibiting discrimination by employers and health insurers.
… is health information and provides a finalized  rule that went into effect March 26, 2013. Employment (Title … on the issue of spouses' genetic information. This amended rule states that it is permissible for wellness programs to …
Policy Issues
Most genetic tests today are not regulated, meaning that they go to market without any independent analysis to verify the claims of the seller.
… advances, genetic and genomic tests are becoming more common in, and out of, the clinic. Yet most genetic tests …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… nearly 500 papillary thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights … investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and …