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Fact Sheets
Data used to estimate the cost of sequencing the human genome over time since the Human Genome Project.
… Institute (NHGRI) has tracked the costs associated with DNA sequencing performed at the sequencing centers funded by … and for establishing the DNA sequencing capacity of the NHGRI Genome Sequencing Program. Here, NHGRI provides an analysis of these data, which gives one view of the remarkable …
Educational Resources
A genetic marker is a DNA sequence with a known physical location on a chromosome.
… Genetic Marker … A genetic marker is a DNA sequence with a known physical location on a chromosome. … Genetic markers are used to track the inheritance of a nearby gene that has not yet been identified, but whose … location is known. The genetic marker itself may be a part of a gene or may have no known function. … A genetic marker …
Educational Resources
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
… Mutation … A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to … Line, Gene … A mutation is a change in the DNA sequence of an organism. Mutations can result from errors in DNA …
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Cytogenetics is the branch of genetics that studies the structure of DNA within the cell nucleus.
… Cytogenetics … Cytogenetics is the branch of genetics that studies the structure of DNA within the cell nucleus. … DNA, Nucleus, Chromosomes, …
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A promoter is a sequence of DNA needed to turn a gene on or off.
… Promoter … A promoter is a sequence of DNA needed to turn a gene on or off. … Deoxyribonucleic Acid … … A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as …
Educational Resources
Polymorphism involves one of two or more variants of a particular DNA sequence.
… Polymorphism … Polymorphism involves one of two or more variants of a particular DNA sequence. … Base Pair, Deoxyribonucleic Acid (DNA), …
Educational Resources
A codon is a trinucleotide sequence of DNA or RNA that corresponds to a specific amino acid.
… Codon … A codon is a trinucleotide sequence of DNA or RNA that corresponds to a specific amino acid. … … ACGT, Gene, Base Pair … A codon is a DNA or RNA sequence of three nucleotides (a trinucleotide) that forms a unit of …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… Each news cycle brings reminders about the importance of science and its critical role in society, and NHGRI … from the institute and the field of genomics. …   The Encyclopedia of DNA Elements (ENCODE) project is an international …
Educational Resources
A tandem repeat is a sequence of two or more DNA base pairs that is repeated in such a way that the repeats lie adjacent to each other on the chromosome.
… Tandem Repeat … A tandem repeat is a sequence of two or more DNA base pairs that is repeated in such a way that the … Non-Coding DNA … A tandem repeat is a sequence of two or more DNA bases that is repeated numerous times in a …
Educational Resources
Epigenetics is an emerging field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism.
… Epigenetics … Epigenetics is an emerging field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism. … Heritability, DNA, DNA …