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News Release
Researchers have found powerful clues to why certain processes and systems in the mouse are so different from those in people.
… from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can … time. The results may offer insights into gene regulation and other systems important to mammalian biology. … for Cancer Research, San Diego. "In general, the gene regulation machinery and networks are conserved in mouse and …
Educational Resources
A repressor is a protein that turns off the expression of one or more genes.
… of one or more genes. … Gene, Gene Expression, Gene Regulation, Messenger RNA (mRNA), Protein, Transcription … A … RNA (mRNA). Repressor proteins are essential for the regulation of gene expression in cells. … Educational …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, Messenger RNA (mRNA), Transcription … A promoter, …
Talking Glossary
Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. regulating the production of proteins that the gene encodes.
Staff
Elena Ghanaim is the Policy Advisor for Data Science and Sharing within the Office of Genomic Data Science (OGDS) at the National Human Genome Research Institute (NHGRI)
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Staff
Cristina Kapustij is the chief of the Policy and Program Analysis Branch at the National Human Genome Research Institute.
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News Release
NHGRI is awarding Genomic Innovator Awards to nine institutions to support the research of 12 early career scientists in the field of genomics. The awards will total up to $27 million over five years.
… Stanford, California Apply CRISPR tools to understand gene regulation related to common, complex diseases.  Audrey E. … medicine, CRISPR, non-coding DNA and RNA sequences, gene regulation, single-cell biology, chromatin state features, …
Research Training
A fellowship that will prepare fellows to use genetic, genomic and pharmacogenomic approaches to advance minority health and health equity.
… Office of Minority Health and Health Equity (FDA OMHHE) , is open for applications. The fellowship … unique experiences by working closely with mentors at both FDA OMHHE, Center for Drug Evaluation and Research (CDER) and … broadly related to: Fellows will gain experience in FDA OMHHE’s and NHGRI's Intramural Research Program efforts …
The Informed Consent Resource
Explore the basic elements of informed consent that are required by the Common Rule and that are relevant to genomics.
… or not possible and what the process is. OHRP and the FDA have both provided guidance related to withdrawal from … the analysis described in the IRB-approved protocol. The FDA guidance also states that destruction of samples that …