Search Results
News Release
Six new grants will support researchers for new computational approaches to search millions of genomic variants for disease susceptibility.
… of funds. They are administered by the National Human Genome Research Institute (NHGRI) and the National Cancer … differences. For the last decade, scientists have used genome-wide association studies (GWAS) to find regions of the … may be transcribed into RNA. Such RNA carries out various regulatory functions in a cell. The researchers have shown …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… colleagues crossbred several strains of mice and examined regulatory DNA and gene activity in brain and other tissue. … research was supported by the Centers for Excellence in Genome Sciences program from the National Human Genome Research Institute (NHGRI) and the National Institute …
News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
… team of genomics researchers has identified new regions of the human genome that are associated with skin color variation in some … skin from the damaging effects of UVR. Because equatorial regions receive approximately two times more UVR than more … Tanzania and Botswana has shed light on regions of the genome not previously associated with skin color. Hands of …
Talking Glossary
Intergenic regions are the stretches of DNA located between genes.
… Intergenic Regions … Intergenic regions are the stretches of DNA located between genes. … Intergenic regions are the stretches of DNA located between genes. In … non-protein-coding and comprise a large majority of the genome. Some intergenic DNA is known to regulate the …
News Release
NIH will fund researchers to develop computational approaches to figure out which differences in DNA make people more susceptible to disease.
… - called genetic variants - in the less-studied regions of the genome that are responsible for regulating gene activity. A … associated with a disease, researchers typically conduct a genome-wide association study (GWAS), which compares the … about which variants in non-protein-coding genomic regions affect disease susceptibility and response to drugs. …
News Release
Researchers identified 13 gene regions that influence cholesterol levels, some of which affected people differently if they are smokers or former smokers.
… researchers and their collaborators identified 13 new gene regions that influence cholesterol levels, some of which … in an analysis can help identify new regions of the genome that affect lipids," said Amy R. Bentley, Ph.D., the … lead author and a staff scientist at the National Human Genome Research Institute's Center for Research on Genomics …
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… into the organization and regulation of our genes and genome … Project is a worldwide effort to understand how the human genome functions. With the completion of its latest phase, … To assess the potential functions of different DNA regions, ENCODE researchers studied biochemical processes …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… data on gene expression, as well as surrogate markers of regulatory elements, in different cell fates or cell states. … disease) of genetic variation, particularly in non-coding regions of the genome. This is a highly significant problem, as the vast … Memorial Sloan Kettering Cancer Center Decoding In Vivo Regulatory Programs Of CD4+ T Lymphocyte Populations In …
Policy Issues
This glossary contains definitions for commonly used terms (such as "bill", "statute", "regulation" and more) found in the Genome Statue and Legislative Database.
… as "bill", "statute", "regulation" and more) found in the Genome Statue and Legislative Database. … Code of Federal Regulations (CFR) that covers a specific regulatory area within a title (one of the 50 major … is further subdivided into parts that cover specific regulatory areas. Large parts may be subdivided into …
Event
On Tuesday, February 6, 2024, the National Human Genome Research Institute hosted an eConsult webinar to provide an overview of three notice of funding opportunities (RFA-HG-24-001, PAR-24-106 and PAR-24-107).
… On Tuesday, February 6, 2024, the National Human Genome Research Institute hosted an eConsult webinar to … On Tuesday, February 6, 2024, the National Human Genome Research Institute hosted an eConsult webinar to … On Tuesday, February 6, 2024, the National Human Genome Research Institute hosted an eConsult webinar to …