Search Results
Staff
Dr. James Inglese is an adjunct investigator in NHGRI's Metabolic Medicine Branch.
… and Screening Technology laboratory within the Division of Pre-Clinical Innovation at NCATS. His postdoctoral … as new anticancer targets. He then acquired expertise in cellular and molecular biology through postdoctoral training … coming to NIH, Inglese led research teams at the Princeton-based combinatorial chemistry biotechnology company …
News Release
NIH is launching a program, Molecular Phenotypes of Null Alleles in Cells (MorPhiC), to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.
… The Molecular Phenotypes of Null Alleles in Cells program will first look at protein-coding genes … The National Institutes of Health is launching a program to better understand the … human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene. The …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… One of the first human studies on how mitochondrial function … future treatments. … In a new study, National Institutes of Health (NIH) researchers found that altered B cell … to fight viral infections, are less able to survive cellular stress. “Our work is one of the first examples to …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… Grantees  Institution (Contact PI) PIs Title University of Maryland, Baltimore Sally Adebamowo*, Michele Ramsay, … Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of Southern … can ensure approaches are feasible at scale using AnVIL. Based on the critical topics identified, this WG will propose …
News Release
Micro-sized technologies are among the approaches researchers will use to develop high quality, low cost DNA sequencing technology.
… Steven Benowitz … A number of micro-sized technologies - such as nanopores and … been an important focus of the program's grants. Nanopore-based DNA sequencing entails threading single DNA strands … the projects will explore the use of microfluidics in DNA library preparation. A library is a collection of stretches …
Talking Glossary
Cell-free DNA testing is a laboratory method that involves analyzing free (i.e., non-cellular) DNA contained within a biological sample, most often to look for genomic variants associated with a hereditary or genetic disorder.
… laboratory method that involves analyzing free (i.e., non-cellular) DNA contained within a biological sample, most … laboratory method that involves analyzing free (i.e., non-cellular) DNA contained within a biological sample, most … is also used for the detection and characterization of some cancers and to monitor cancer therapy. … Cell-free …
Educational Resources
A ribosome is a cellular particle made of RNA and protein that serves as the site for protein synthesis in the cell.
… Ribosome … A ribosome is a cellular particle made of RNA and protein that serves as the … Acid (RNA) … A ribosome is an intercellular structure made of both RNA and protein, and it is the site of protein …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in February 2021.
… Vision Scientific American – A Vision for the Next Decade of Human Genomics Research Forbes - How Human Genome … Project GTEx Program Website List of GTEx Publications 27 Library of Integrated Network-based Cellular Signatures (LINCS) LINCS …
The Genomics Landscape
In the February 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the new director of NHGRI's Division of Genome Sciences.
… your attention to a request for information from the All of Us  Research Program. The deadline for submitting use case … and Health in Africa (H3Africa) Initiative, and the Library of Integrated Network-Based Cellular Signatures (LINCS). As …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in September 2020.
… Fellow Genetics and Education Fellow 2 30 th  Anniversary of Human Genome Project Launch Interviews with Genomics … and Career Development 33 2020 Genomic Innovator Awards 34 Library of Integrated Network-based Cellular Signatures (LINCS) LINCS …